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Coordinates with Cancer Immunology, Protein Chemistry, Antibody Engineering, and Translational Oncology groups to advance lead molecules of the projects. Supports biochemical and cellular characterization of protein therapeutics for immuno-oncology.
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The Susa lab is starting the Department of Pharmaceutical Chemistry at UCSF and is seeking applicants for a research technician position using structural biology, membrane protein biochemistry, cell biology, and protein engineering to understand fundamental mechanisms of transmembrane signaling within the human immune system.
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Solid fundamental knowledge of enzyme mechanisms, protein characterization, and assay development / optimization. Requires BS or MS in Chemistry, Chemical Biology, Biochemistry, Molecular Biology, (Bio)chemical Engineering, or related field.
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Experience with the following is preferred: lab automation (especially automated liquid handling, e.g. Hamilton or similar), immunoassays, polymer chemistry, microfluidics, design control including V&V / Gage R&R, project management, quality management system, and clinical environments.
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Perform in vitro DMPK assays- stability, drug permeability, and protein binding. BS/BA degree in biology, chemistry, or related science and 2+ years of experience in a DMPK or biology laboratory, including hands-on experience with DMPK-related technology and methodologies such as: automation and LC-MS/MS.
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Some background in protein engineering, immunology, virology, and/or assay development. Strong background in protein engineering, immunology, virology, and/or assay development. PhD in Biology, Molecular Biology, Microbiology, Immunology, Chemistry, Bioengineering, or related field.
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This role demands expertise in food science, material science, polymer chemistry, and protein chemistry, along with a keen curiosity and willingness to explore beyond traditional disciplinary boundaries (think sensory testing, food science, etc.
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We advance new concepts in imaging, proteomics, drug discovery, and catalysis by drawing from core disciplines of inorganic, organic, and biological chemistry. We are advancing a new paradigm of transition metal signaling, where metal nutrients like copper and iron can serve as dynamic signals to regulate protein function by metalloallostery, going beyond their traditional roles as static active site cofactors.
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The ideal candidate will have a track record of demonstrated skills and experience in managing antibody generation, production and characterization including but not limited to upstream protein production (mammalian cell culture and harvest experience), and downstream protein purification and analytical assessment of candidate molecules for purity, developability, and stability.
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The successful candidate is expected to have experience in protein chemistry and biophysical characterization of biologics using a variety of analytical tools – chromatographic, electrophoretic, light scattering and other analytical methods.
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Develops, validates and executes biochemical and cell-based assays to characterize and screen biologic therapeutics in vitro and ex vivo, to support lead-finding/optimization efforts. Research Associate I , working in.
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Solid knowledge of medicinal chemistry principles, including DMPK, as well as the understanding of IP and its analysis is expected. Experience in a broad variety of computational techniques is essential, particularly molecular docking, pharmacophore development, library design and analysis, machine learning methods, and protein-ligand simulation.
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Throughput cell analysis, phenotyping, protein chemistry and antibody cell analysis. throughput cell analysis, phenotyping, protein chemistry and antibody cell analysis. named Ghost Cytometry (GC) which combines high-speed imaging and machine learning to analyze and.
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In this camp, we will take a multi-disciplinary approach to learning and incorporate studies in chemistry, oceanography, ecology, and marine biology to learn about Earth's amazing seas and the animals and plants that inhabit them.
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We're hiring a full-time Research Assistant to support molecular biology, cell and tissue culture, histology, and chemistry experiments. Experience in protein engineering. We're hiring a full-time Research Assistant to support molecular biology, cell and tissue culture, histology, and chemistry experiments.
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protein chemistry jobs in Oakland, CA
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