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The specific role(s) of the specialist will include: 1) validating CRISPR-ki cell lines and primary cells; 2) affinity purification, chemical cross-linking, and sample preparation for mass spectrometry (MS) analysis; and 3) enzymatic and virological-based assays for functional characterization of protein components.
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This role demands expertise in food science, material science, polymer chemistry, and protein chemistry, along with a keen curiosity and willingness to explore beyond traditional disciplinary boundaries (think sensory testing, food science, etc.
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Hands-on experience with DMPK assays, including screening, plasma protein binding, and. chemistry, pharmacology, and toxicology, to support drug discovery and development projects. Plasma Protein Binding Studies: Conduct experiments to determine the binding affinity of.
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Lycia Therapeutics is seeking a team-oriented Principal/Senior Scientist with a strong pharmacokinetics background to help develop novel small molecule and protein-based therapeutics. Lycia Therapeutics, Inc. is a biotechnology company leveraging its lysosomal targeting chimera (LYTAC) platform from Founder and Chemistry Nobel Laureate 2022, Carolyn Bertozzi, to discover and develop first-in-class therapeutics that degrade extracellular and membrane-bound proteins.
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Proficient in protein-based assay development including ELISA, enzymatic activity assay, AlphaLisa, etc. Strong expertise in protein-peptide, protein-small molecule or protein-protein interaction characterization, including SPR, BLI, FP (fluorescence polarization), Mass spec, DSF, ITC, etc.
$127,000 - $135,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Some background in protein engineering, immunology, virology, and/or assay development. Strong background in protein engineering, immunology, virology, and/or assay development. PhD in Biology, Molecular Biology, Microbiology, Immunology, Chemistry, Bioengineering, or related field.
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They bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.
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The successful candidate is expected to have experience in protein chemistry and biophysical characterization of biologics using a variety of analytical tools – chromatographic, electrophoretic, light scattering and other analytical methods.
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Identify relative risk of protein adsorption and degradation under various formulation conditions using analytical techniques, such as: quartz crystal microbalance with dissipation (QCM-D); size exclusion chromatography (SEC); particle characterization (micro-flow imaging); and ion-exchange chromatography (IEX.
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Skills: Molecular Biology, Cell Biology, Biology, Chemistry, Chromatography, Protein Purification, Cell Cultures, Manufacturing Operations. Experience in cell culture and/or protein purification.
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Perform protein, peptide, small molecule, nucleic acid, glycan analysis and characterization by mass spectrometry, using RPLC-MS and RPLC-MS/MS, native-MS and other hyphenated MS analytical capabilities to support the diverse early-stage pipeline.
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Preferred Skills: State-of-the-art transient and stable protein expression experience Relevant bioreactor experience Hands-on experience with automation and liquid handlers like Tecan Freedom Evo and Hamilton Microlab Star Knowledge of cell biology, cell engineering, molecular biology, recombinant protein purification and protein characterization is preferred Important information: This position is recruited for by a remote Kelly office , not your local Kelly branch.
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Throughput cell analysis, phenotyping, protein chemistry and antibody cell analysis. throughput cell analysis, phenotyping, protein chemistry and antibody cell analysis. named Ghost Cytometry (GC) which combines high-speed imaging and machine learning to analyze and.
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Graduate degree in a relevant molecular discipline (organic, oligonucleotide or peptide chemistry; protein engineering) Reporting to the CSO, you will lead a team of drug discovery professionals in areas including: medicinal chemistry; DNencoded chemical library design, synthesis and screening; complex biologics (including antibody-drug conjugates, ADCs); oligonucleotides; analytical sciences; PKDM; protein sciences and structural biology.
$300,000 - $360,000 a yearFull-timeExpandApply NowActive JobUpdated 25 days ago - UpvoteDownvoteShare Job
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Solid knowledge of medicinal chemistry principles, including DMPK, as well as the understanding of IP and its analysis is expected. Experience in a broad variety of computational techniques is essential, particularly molecular docking, pharmacophore development, library design and analysis, machine learning methods, and protein-ligand simulation.
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protein chemistry jobs in San Francisco, CA
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