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Proficiency with basic molecular biology techniques: plasmid design, cloning, primer design and PCR, DNA isolation, gel electrophoresis, Sanger sequencing analysis. In our Brighton/Boston labs, RNA biology meets today's cutting-edge genomics, computational biology, and deep-sequencing technologies to create a new class of medicines that address the underlying causes of disease.
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Volta Labs is an MIT spin-off that has unlocked powerful new DNA sequencing capabilities by developing novel fluidic technology. Building off of this core technology, Volta has created a product that streamlines DNA sequencing sample prep.
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Perform serologic, molecular and immunologic procedures that may include, but are not limited to, DNA extraction, PCR amplification, sequence-based typing, STR analysis, probe hybridization/detection, cytotoxic crossmatching, antibody screening/identification by Luminex and/or ELISA assays and other procedures as defined.
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Solid tumor tissue and cell free DNA next-generation sequencing assays and assay validation. Genomics and/or genetics including technology platforms, bioinformatics and somatic variant classification and functional interpretation of somatic variants according to established professional guidelines (e.g., AMP, ACMG, ASCO, NCCN or ESMO.
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Optimize pilot plant and pre-clinical production performance to allow for fast, flexible processing of multiple manufacturing processes including plasmid DNA prep, mRNA transcription and purification, and LNP formulation, and oligonucleotide synthesis.
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If required, are you open to eligible /registered candidates] PREFERRED BUT NOT REQUIREDAre you seeking a generalist [proficient in testing in all Chemistry, Hematology, Urinalysis, Coagulation] or are you seeking a Micro Lab worker with Molecular backgroundGENERALIST WITH BLOOD BANK EXPERIENCEWhat department will this technical position support [Micro lab, Core lab, DNA sequence, etc.
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Expertise in molecular biology, cell culture techniques and production of biomacromolecules such as mRNA, plasmid DNA, self-amplifying mRNA (saRNA), proteins, or AAV. Stay aware of the process technology advancements and new DNA/RNA modalities through publications, presentations, patents, and industry workshops.
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Deep experience with methodologies and tools for yeast (S. cerevisiae and/or P. pastoris) strain engineering, e.g. DNA assembly, transformation, integration, sequencing, bioinformatics, etc. Leverage knowledge of enzyme kinetics and assay development tools to develop methods for high- and ultrahigh-throughput screening and validate results using pertinent analytical methods (e.g. LC- and GC-MS.
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Automated Liquid Handler Knowledge : Experience and proficiency in operating and maintaining automated liquid handling systems, such as Agilent Bravo, to perform tasks like NGS (Next-Generation Sequencing) library preparation, RNA/DNA isolation, and sample processing.
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Independently performs non-routine, highly specialized experimental procedures, such as performing cell culture, genomic DNA isolation from tissues and cells, qRT-PCR, and other cell biology and molecular biology experiments.
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We are looking for a senior lab technician with a background in biological research, single cell analyses via flow cytometry, molecular techniques, and the ability to independently manage lab operations in a new and dynamic research environment.
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Ability to develop, evaluate, and implement workflows for technology, optimize and standardized existing techniques and workflows with respect to experimental HT mRNA generation process workflow including DNA & IVT-RNA production, and in vitro/in vivo screening is desired.
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Possess professional knowledge of Federal, State and local regulations pertaining to Center of Disease Control Prevention (CDC) and National Institutes of Health (NIH) guidelines for biosafety as they apply to infectious agents, recombinant DNA and bloodborne pathogens.
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Oxford Nanopore's sequencing platform is the only technology that offers real-time analysis (for rapid insights), in fully scalable formats from pocket to population scale, that can analyze native DNA or RNA and sequence any length of fragment to achieve short to ultra-long read lengths.
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FES technology will enable the reading and writing of DNA for many industries, including industrial synthetic biology and precision medicine, as well as emerging applications of DNA for data information storage, nanomachines, and bio-based electronics.
$100,000 - $200,000 a yearFull-timeExpandApply NowActive JobUpdated 6 days ago
dna job Company: Remote Career Jobs in Waltham, MA
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