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Accountability for the development and maintenance of batch records, SOPs and training materials for the DNA processes. Lead a team of Managers and Technical Specialists to safely produce DNA Plasmid to support mid-to-late-stage clinical programs.
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Capabilities within the Group include molecular, cellular, and synthetic biology; microbiome engineering; rapid DNA sequencing; bioinformatics; microfluidics; mass spectrometry; laser spectroscopy; and organic chemistry.
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Familiarity of and experience working with DNA manipulation techniques, enzymatic reactions, and sequencing chemistry. Prepare the Next Generation Sequencing (NGS) library. The Molecular Technologist I performs procedures in a complex patient sample testing process with limited supervision.
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With a combination-focused pipeline that exploits the power of six scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy, and Epigenetics) to help address unmet clinical needs in a host of cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death.
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This includes immunological techniques (immune cell isolation, assays of stromal, myeloid, and T cell function, cytokine ELISA assays, multiparameter flow cytometry), molecular biology procedures (PCR, RNA and/or DNA preparation from tissues, as well as bulk and single-cell RNASeq.
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Experience with RNA/DNA NGS and automation is a plus. Molecular biology laboratory techniques including: bacterial culture, PCR, cloning, protein blot analysis, assay development (western blot, ELISA, luminescence), and phage propagation.
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Life Sciences Associate Attorney will be responsible for providing legal counsel and support on patent prosecution and counseling projects within the life sciences sector, particularly focusing on emerging companies involved in antibodies, DNA or RNA therapeutics, chemical biology, gene-editing, and related areas.
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At least 3 to 5 years molecular or genomic lab experience including DNA/RNA extraction, library preparation and NGS analysis. The selected candidate will perform computational analysis of next generation sequencing data including single nucleotide variations, somatic copy number alterations, indels, expression profiling, and biological pathways using in house algorithms and prepare report for final review.
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Illustrative subject matter concerns patent prosecution and counseling projects with emerging companies focused on antibodies, DNA or RNA therapeutics, chemical biology, gene-editing, etc. Intellectual Property - Life Sciences - Midlevel/Senior Associate Attorney – Boston OfficeRequirements:Boston, Massachusetts office of an AMLaw 100 firm is seeking a midlevel to senior associate with 1-7 years of patent prosecution experience in a biotechnology practice and an advanced degree, preferably a Ph. D., in a life sciences technology area, e.g. molecular biology, immunology, biochemistry, cell biology, and the like.
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Known for its rich heritage and unique brand DNA, Kate Spade New York offers a distinctive point of view and celebrates communities of women around the globe who live their perfectly imperfect lifestyles.
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Proven expertise in molecular biology techniques, including DNA cloning, DNA/RNA extraction, qPCR, western blotting. Perform gel electrophoresis, Western blot, and DNA/RNA extraction from cells and tissues.
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Experience with clinical research, mouse handling, and standard molecular biology techniques (DNA/RNA extraction, cell cultures, PCR, western blot, immunostaining) ·Highly motivated, well-organized, and flexible·Excellent oral and written communication skills.
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Prepares DNA or RNA from clinical specimens, which includes handling of tissues and blood samples, centrifugation, spectrophotometry, gel electrophoresis and robotic instrumentation. Protocols utilize a variety of molecular assays that are constantly evolving as the discipline develops, but includes PCR, RT-PCR, QRT-PCR, Hologic Invader Assay, capillary gel electrophoresis, Sanger sequencing, Pyrosequencing, multiplexed liquid bead microarray (Luminex), melt curve analysis (Lightscanner), Hologic Aptima HPV assay, Next Generation Sequencing and Mass Spectrometry.
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Proficient in cloning techniques (standard, Gibson, Golden Gate) and a wide range of molecular biology protocols (including DNA/RNA purification, various PCR methods, and NGS library prep). Conduct plasmid cloning and apply molecular biology techniques including DNA/RNA isolation, cDNA synthesis, and quantitative PCR methods.
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Proficient in common molecular cloning techniques and sequencing (E.g., DNA/RNA isolation, PCR, qPCR, NGS library generation), RASyn’s platform integrates computational protein design and engineering, machine learning, synthetic biology, and single cell sequencing and will enable cheaper, faster, and larger scale production and optimization of biologics, enzymes, and biomolecule libraries.
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dna job Company: Remote Career Jobs in Waltham, MA
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