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Lead preclinical pharmacology including in vitro and in vivo assay development and execution across the organization. A PhD or equivalent with a focus on pharmacology, neuroscience, molecular biology, or cellular biology.
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Strong knowledge of model-informed drug development, DMPK-Clinical Pharmacology concepts, and regulatory requirements. A Ph. D. or PharmD with a minimum of 10 years of industry experience in pharmaceutical sciences, pharmacokinetics, clinical pharmacology, chemistry, or related fields.
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This research group consists of UCSF faculty whose studies are focused broadly on clinical investigation of the pharmacology and cardiovascular toxicities of tobacco, electronic cigarettes, and cannabis products.
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The Lab Coordinator will join Clinical Pharmacology Research Laboratory under the Division of Cardiology School of Medicine at ZSFG to conduct nicotine and tobacco related researches in human. The Division of Cardiology at ZSFG is home for an active clinical pharmacology research program led by Dr. Neal Benowitz, who is also an attending physician in our cardiology clinic.
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Lab Coordinator - Clinical Pharmacology. The Lab Coordinator will perform advance chromatographic and mass spectrometric analysis, such as Gas Chromatography (GC), Liquid Chromatography (HPLC), Gas Chromatography-Mass Spectrometry (GCMS), Gas Chromatography-Tandem Mass Spectrometry (GC-MS/MS), and Liquid Chromatography with Tandem Mass Spectrometry (LC-MS/MS); organize experimental data and keep detailed records of experiments; prepare and present reports independently.
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Strong knowledge of pharmacokinetics and modeling, pharmacodynamic principles, ADME concepts, bioanalytical principles, regulatory guidelines and clinical pharmacology requirements in late stage clinical development.
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Effective cross-functional collaboration, especially with Institutes of Science, In Vivo Pharmacology and DMPK, in the optimization of drug leads and candidates. PhD in Toxicology, Pharmacology or related sciences (or DVM) and a minimum of 15-20+ years of industry experience in Pathology/Toxicology.
$324,700 - $439,300ExpandApply NowActive JobUpdated Yesterday - UpvoteDownvoteShare Job
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Planning and execution of mechanistic PKPD analyses to integrate knowledge of drug design parameters, disease pharmacology, physiology, pharmacokinetics and pharmacodynamics, and to optimize selection doses and preclinical study designs.
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The Clinical Pharmacology, Modeling & Simulation Department at Amgen is seeking a Principal Scientist at its South San Francisco, CA location. PhD (in Pharmacokinetics or Pharmaceutical Sciences or Pharmacology or Chemical Engineering or equivalent professional degrees e.g. MD, PharmD.
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Reporting to the VP and Head of Research, the Senior Director, Integrative Biology will be the senior in vivo scientist in the pre-clinical research organization overseeing pharmacology and toxicology experiments.
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In this vital role you will be responsible for the development and implementation of the Quantitative Clinical Pharmacology, Modeling and Simulation strategies for cutting-edge novel modalities including Bi-specific T-cell engagers, Bi-specific antibodies, oncolytic viruses, antibody-drug-conjugates, CAR-T cells-based therapies in addition to small molecule & mono-clonal antibodies.
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Collaborate with In Vivo Pharmacology and DMPK on development of translational PKPD models. Develop and integrate timelines and budgets for clinical pharmacology activities with overall company timelines and goals, in close coordination with project management, clinical science, CMC, DMPK, nonclinical development, regulatory affairs and other stakeholders.
$262,000 - $321,000 a yearFull-timeExpandApply NowActive JobUpdated 3 days ago - UpvoteDownvoteShare Job
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PhD, PharmD or equivalent in Pharmacokinetics, Pharmacology, Bioanalytical or related field with at least 5+ years of experience in Clinical Pharmacology, DMPK or related disciplines required.
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Understanding of standard drug development process, defining in vivo pharmacology, assessing PKPD and deriving margins to provide clinical starting doses. Conceptualize and design strategies for drug discovery using insitro's platforms from hit to lead using industry standard preclinical pharmacology models and standard drug development models by applying insights exposed by insitro's unique target discovery credentialization.
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Excellent working knowledge of clinical pharmacology (pharmacokinetics, pharmacodynamics, translational medicine) and drug development principles. Serve as the study director for Phase 1 studies including first-in-man, biopharmaceutics, drug-drug interactions, special populations, and proof-of-pharmacology/concept studies, and be accountable for timely and high-quality execution of all clinical studies under his/her responsibility in the Pliant Portfolio.
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pharmacology job Company: Genesis Research in San Francisco, CA
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