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Collaborating with tech transfer team to ensure successful hand-off of assay, reagent scale-up and QC processes. They will be core collaborators as part of the Assay Development team with full cross-disciplinary team of system integration engineers, algorithm developers and technical operations engineers to ensure V&V studies meet requirements.
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Good knowledge of cell-based methods associated with bioanalytical analytical method development (e.g. TCID50, Potency assay, viral transduction, and ELISA methods) preferred. Familiar knowledge of GLP and GMP requirements as they pertain to protein and gene therapy process development and Quality Control (QC) testing is a plus.
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Determines appropriate assays and vendors for clinical biomarkers, and manages outsourcing of biomarker assay development and validation partnering with Translational Sciences colleagues when applicable.
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Deep understanding of in vitro assays and assay development. Support assay design, optimization, validation, and data analyses. Strong background in designing and conducting multi-color flow cytometry, as well as analyzing FACS-based experiments.
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Familiar with molecular assay development, genetic sequencing principles or sequencing devices. Assay Development (Remote Potential) role based in the United States of America is: $167,200 - $250,800.
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The incumbent will be responsible for drug screening, cell-based assay development, and biomarker discovery. Perform cell biology and molecular biology including primary and tumor cell culture, lentiviral transductions, RNA and protein preparation from cells and tissue, RT-PCR, western blotting, and ELISA. Some training may be provided.
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Human whole blood, primary human and mouse/rat leukocyte isolation, cellular activation and differentiation, cytokine assays (MSD, ELISA), confocal/image-related techniques, etc. Familiarity with Client FACS and Spectral flow cytometry.
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Working in a team setting, the Research Scientist I, will primarily be involved in Research and Development projects serving as a technical lead in translating research ideas and concepts into the product development pipeline towards development of diagnostic assay products.
$93,000 - $149,000 a yearExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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Independently manage molecular cloning experiments and assay development to construct DNA constructs and perform functional characterizations in microbial and plant systems. Knowledge of gene editing and analytical chemistry (e.g., GC, HPLC) is favorable, along with a background in protein interaction assays.
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Experience with experimental design& planning, assay development, statistics, DOE techniques, data analysis methods and software (JMP, Python, or Matlab preferred). As a key member of the material science group within Dexcom's research and development organization, the Staff membrane and formulation scientist is responsible for developing and validating novel membrane designs and formulations to support next generation biosensor products.
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Experience with super-resolution imaging techniques, microscopy, cell sorting, antibody based assays, biological sample preparation, image acquisition and data analysis, and/or cell based assay development.
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Assay types of interest include both protein-ligand and protein-protein interaction techniques, including but not limited to SPR, GCI, DSF, ASMS, MST, proximity, and enzymatic activity assays, among other biochemical and biophysical approaches.
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Independently design experiments with an exceptional variable control for lateral flow assay development and optimization. Eli is looking for an R&D Scientist I. You will be a key member of our R&D team, helping to discover new ways to improve current and future iterations of our assay technology.
Full-timeExpandApply NowActive JobUpdated 9 days ago - UpvoteDownvoteShare Job
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Areas of research include (1) Small Molecule/Fragment screens toward difficult to drug protein targets, (2) Structure activity relationship (SAR) assay support for advanced small molecule programs, (3) DNA encoded libraries (DEL) screen hit conformation and SAR assay support, (4) Evaluation of large molecule (Proteins, Antibody, Fab, Peptides etc.
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As a CLS/CGMBS at Inocras, you will be performing clinical laboratory testing for a whole genome Next Generation Sequencing (NGS) assay in order to provide doctors and patients complete genetic profiles for cancer and rare diseases.
ExpandApply NowActive JobUpdated 10 days ago
assay job in San Diego, CA
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