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This position is based in San Diego, CA. Depending on experience, the scientist will expand molecular and product specific assay development working with the Gene Therapy Research and Development team.
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HD Biosciences, Inc. (US), a WuXi AppTec Company, is seeking a highly motivated and established Executive Director with deep and broad expertise in in vitro pharmacology including assay development, HTS/SAR, and compound management to join us.
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Independently manage molecular cloning experiments and assay development to construct DNA constructs and perform functional characterizations in microbial and plant systems. Knowledge of gene editing and analytical chemistry (e.g., GC, HPLC) is favorable, along with a background in protein interaction assays.
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Areas of research include (1) Small Molecule/Fragment screens toward difficult to drug protein targets, (2) Structure activity relationship (SAR) assay support for advanced small molecule programs, (3) DNA encoded libraries (DEL) screen hit conformation and SAR assay support, (4) Evaluation of large molecule (Proteins, Antibody, Fab, Peptides etc.
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Experience with primary neurons and iPSC-derived neurons, and their use in assay development, is beneficial. in collaboration with AbbVie About the Role: Plays a key leadership role in developing our in vitro and in vivo strategies towards target identification and drug discovery, through to clinical candidate selection.
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As a CLS/CGMBS at Inocras, you will be performing clinical laboratory testing for a whole genome Next Generation Sequencing (NGS) assay in order to provide doctors and patients complete genetic profiles for cancer and rare diseases.
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Additional responsibilities will include assay development and optimization in complex cellular and biochemical settings, and the use of Vividion's proprietary chemical proteomics platform. Experience in multi-color flow cytometry, Western blot, ELISA/Luminex/MSD.
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In addition to the utilization of portable, rapid assay technologies to identify pathogens in the field, test specimens and limited epidemiologic data, when approved by the Institutional Review Board (IRB), are provided to the NHRC laboratory where diagnostics and, in some instances, in-depth pathogen characterization is conducted.
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Assay Development: Focus on feasibility, verification and validation of new assays for commercialization. May participate in assay development related meetings. Assay Development: Focus on feasibility, verification and validation of new assays for commercialization.
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The incumbent will be responsible for drug screening, cell-based assay development, and biomarker discovery. biology techniques (Protein, DNA and RNA isolations, Western blot, qRT-PCR , Flow Cytometry.
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Hologic is seeking a Sr. Manager, PMO who will be dedicated to program management of new assay development and instrumentation/engineering project and programs. Experience running programs that included assay development and validation.
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Biochemical techniques including quantitative Polymerase Chain Reaction (qPCR)/Digital Droplet PCR (ddPCR), Enzyme-Linked Immunosorbent Assay (ELISA), western blotting, gel-based assays, etc. High-Performance Liquid Chromatography (HPLC), Liquid Chromatography Mass Spectrometry (LCMS), Fragment Analyzer, Capillary Electrophoresis.
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Working in a team setting, the Senior Research Associate II, will primarily be involved in Research and Development projects actively participating in translating research ideas and concepts into the product development pipeline towards development of diagnostic assay products.
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Familiar with molecular assay development, genetic sequencing principles or sequencing devices. As Associate Director of Program Management, you will be a Product Development Program Manager for a variety of Clinical Next Generation Sequencing projects within Illumina's cutting-edge Oncology portfolio.
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May participate in assay development meetings. May participate in assay development meetings. Clinical Affairs/Novel Biomarker Discovery: Focus on early feasibility and novel biomarker discovery.
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assay job in San Diego, CA
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