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Research Associate I-II, Discovery Chemistry – Oligonucleotide (Purification) Characterization and purification of novel oligonucleotides using HPLC and LCMS. We are looking for candidates as Research Associate I or II, Oligonucleotide Chemistry to join our discovery chemistry team to advance cutting-edge RNA editing drug discovery programs.
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Experience in mammalian cell culture, protein expression platforms (i.e. HEK, CHO, or E. coli), and an understanding of protein purification techniques is preferred. Skills in molecular biology including DNA isolation and purification, construct design, and cloning are required.
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Proficient in all aspects of modern peptide synthesis, protein bioconjugation, peptide and protein purification and analysis· Proficient in all aspects of modern peptide synthesis, protein bioconjugation, peptide and protein purification and analysis.
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Design, synthesize and characterize peptides, small proteins and chemically-modified analogs using state-of-the-art synthesis, bioconjugation, purification, analytical and biophysical techniques.
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The Research Associate will be responsible for conducting hands-on experiments including but not limited to molecular biology, mammalian cell culture, recombinant protein purification and characterization.
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Significant expertise in protein biochemistry, including recombinant protein expression, purification and characterization is a plus. Successful candidates will be talented, highly motivated, creative individuals, able to work semi-independently, and have a strong background in either computational protein design, immunology, or protein biochemistry with an emphasis on immunology.
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The Fleet Solutions group provides turnkey overhaul / repair, testing, and parts sales for air compressors, main propulsion steam turbines, valves, steam turbine generators, auxiliary turbines, dehydrators, pumps, strainers, PLCs, blowers, and water purification.
$49,000 - $71,700 a yearFull-timeExpandApply NowActive JobUpdated 3 days ago - UpvoteDownvoteShare Job
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Utilize knowledge of aquarium husbandry techniques, including taxonomy, record keeping, aquarium filtration, aquarium theory, and emergency procedures. Assist with animal collecting and repairs to aquarium filtration systems.
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Design and execute laboratory experiments to optimize and characterize conjugation chemistries and downstream purification processes for peptide-based bioconjugates. The candidate will be responsible for development and management of manufacturing and purification processes will collaborate with internal CMC groups and external CDMOs to ensure quality an on-time delivery of API’s Provides project management support for CMC programs or Chemical Development projects, may lead work streams or projects within Chemical Development.
$106,400 - $154,325 a yearFull-timeExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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Proficient in all aspects of modern peptide synthesis, bioconjugation, purification and analysis; capable of immediate independent laboratory work on solid- and solution-phase chemistry. Principal Scientist, Peptide / Bio-organic Chemistry.
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Experience with T-cell characterization methods (flow cytometry (multiparametric and ICS), cell-based assays (proliferation, cytotoxicity), ELISA, multiplex cytokine assays,purification using MACS system, etc.
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Basic tissue culture and purification responsibilities include performing cell culture work, antibody purification, conjugation, and associated quality control steps including purity analysis, isotype testing, mycoplasma detection, and specificity measurement by assigned methods.
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The successful candidate will perform a variety of techniques, including cloning and expression of recombinant proteins, tissue culture, protein purification, and preparation for mass spectrometry analysis.
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Experience with diverse purification approaches for different antibody formats, analytical characterization (SEC-HPLC, cGE, mass spec, cIEF, SEC-MALS), and developability assessment (thermal stability, poly specificity, hydrophobicity, forced degradation, serum stability) is required.
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Responsible for Installation, and qualification of Automation systems for batch processing tanks, solvent recovery system, filter dryers, HPLCs, filtration systems, Lyophilizers, ultra-low freezers, HVAC, solvent distribution and recovery systems, compressed air, purified water, and wastewater system.
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purification filtration jobs Company: Genomatica in Coronado, CA
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