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The Fleet Solutions group provides turnkey overhaul / repair, testing, and parts sales for air compressors, main propulsion steam turbines, valves, steam turbine generators, auxiliary turbines, dehydrators, pumps, strainers, PLCs, blowers, and water purification.
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Experience with T-cell characterization methods (flow cytometry (multiparametric and ICS), cell-based assays (proliferation, cytotoxicity), ELISA, multiplex cytokine assays,purification using MACS system, etc.
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Knowledge of methods for protein purification, conjugation to fluorochrome and haptens, flow cytometry, immunochemical and immunoassay techniques highly desirable. Knowledge of methods for protein purification, conjugation to fluorochrome and haptens, flow cytometry, immunochemical and immunoassay techniques highly desirable.
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The intern will work closely with R&D oligonucleotide team and primary duties will include, but not limited to synthesis, deprotection, and purification of oligonucleotides, as well as analysis and characterization of oligonucleotide products.
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The Research Associate will be responsible for conducting hands-on experiments including but not limited to molecular biology, mammalian cell culture, recombinant protein purification and characterization.
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Significant expertise in protein biochemistry, including recombinant protein expression, purification and characterization is a plus. Successful candidates will be talented, highly motivated, creative individuals, able to work semi-independently, and have a strong background in either computational protein design, immunology, or protein biochemistry with an emphasis on immunology.
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Excellent proficiency in molecular biological techniques including DNA purification, molecular cloning, protein purification. Calibr-Skaggs supplements the discovery process with the required disciplines for drug development which include chemical library screening, medicinal chemistry, in-vivo model optimization, formulation development, pharmacokinetic and toxicologic expertise, and early clinical development.
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Must have direct experience with oligo synthesis equipment (e.g., AKTA Oligopilot, AKTA Pilot/Beckman Purification systems, Dionex/Vanquish HPLC analytical systems, rotary evaporators). The main responsibility for the Synthesis and Production Microbiology Supervisor is to lead and oversee all production activities associated with oligo synthesis and production microbiology in a multi-product cGMP facility.
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Basic tissue culture and purification responsibilities include performing cell culture work, antibody purification, conjugation, and associated quality control steps including purity analysis, isotype testing, mycoplasma detection, and specificity measurement by assigned methods.
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Proficient in all aspects of modern peptide synthesis, bioconjugation, purification and analysis; capable of immediate independent laboratory work on solid- and solution-phase chemistry. Design, synthesize and characterize peptides, small proteins and chemically modified analogs using state-of-the-art synthesis, bioconjugation, purification, analytical and biophysical techniques.
$106,400 - $154,325 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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The successful candidate will perform a variety of techniques, including cloning and expression of recombinant proteins, tissue culture, protein purification, and preparation for mass spectrometry analysis.
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Performing DNbased labwork independently such as: aqueous chemical reactions on DNA–small molecule conjugates; DNA ligation or other molecular biology techniques; purification of DNA conjugates with High-Performance Liquid Chromatography (HPLC) or other techniques; analysis of DNsmall molecule conjugate compositions through mass spectrometry, electrophoresis, DNA quantitation and other relevant methods.
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Collaborate with cross-functional partners, such as Supply Chain, Manufacturing Sciences, Manufacturing Technical Support, Quality Assurance, Quality Control, Validation and Facilities to accomplish organizational objectives (e.g., meeting commercial demand, new process transfers, new manufacturing area commissioning and validation.
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Proficient in all aspects of modern peptide synthesis, protein bioconjugation, peptide and protein purification and analysis. Principal Scientist, Peptide Protein Chemistry. Proficient in all aspects of modern peptide synthesis, protein bioconjugation, peptide and protein purification and analysis.
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May perform enzymatic reactions, utilizing purification systems, authoring and implementing SOPs, and documenting action in batch records. May perform Oligo synthesis using automated synthesizers, purification of custom Oligonucleotides (RP, AX, IP, PAGE), Post purification reactions (Amine/ Thiol conjugations), 5’ Cap and 5’ Triphosphate.
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purification job in Coronado, CA
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