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A qualified candidate will assist in experimental research tasks using standard molecular biology techniques (DNA/RNA extractions, PCR, cloning, DNA/protein quantification, DNA and SDS PAGE electrophoresis.
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As a Senior Scientist, you will work within the RNA Medicine team to develop a novel nucleic acid drug development platform. You have strong hands-on experience with molecular biology and protein techniques including, but not limited to, nucleic acid isolation, qPCR, RT-qPCR, western blots.
Full-timeExpandApply NowActive JobUpdated 10 days ago - UpvoteDownvoteShare Job
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Isolation of protein, RNA, and DNA from cultured cells and isolated murine ocular tissues with subsequent analyses; will involve numerous isolation kits as well as familiarity with standard methods for western blot, PCR, and ELISA assays.
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RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes.
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Plasmid assembly and protein purification, and cloning. Perform various techniques in molecular biology such as: RNA extraction and analysis. Flow cytometry, single cell sequencing, special proteomics and transcriptomics (training will be available), and various cellular and molecular biology techniques will be an essential part of this research.
ExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Trained to perform genetic, biochemical, molecular, and cellular techniques in experimental disease model systems including but not limited to: DNA/RNA/protein extraction and quantification, SDS-PAGE/immunoblot, PCR, real-time qPCR, immunofluorescent and immunohistochemistry, biochemical assays, cell culture, rodent colony management, transgenic rodent models, rodent exposures, and mammalian tissue collection and processing.
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General duties will include breeding, weaning and genotyping genetically altered mice, assisting in collection, processing and cataloging tissue samples from mice, culture of primary cells, RNA and protein extraction, performing various biologic analyses (gel electrophoresis, Western blotting, ELISA, immunohistochemistry and immunocytochemistry, qRT-PCR, etc.
$31,561 - $58,393 a yearFull-timeExpandApply NowActive JobUpdated 16 days ago - UpvoteDownvoteShare Job
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Strong RNA biology knowledge including genetic element (UTRs, codon, structure, IRES) optimization for enhanced protein translation. Develop RNA purification, characterization, and analytical methods to generate therapeutic grade material for in vitro and in vivo studies.
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The methods used in our laboratory include tissue culture, exposure of cells to cigarette smoke and e-cigarettes, isolation of cells from murine and human tissues, transfections, RNA and protein isolation, quantitative PCR, Western blotting, histology, immunofluorescence, fluorescence microscopy, flow cytometry and others.
$18.29 an hourFull-timeExpandApply NowActive JobUpdated 25 days ago - UpvoteDownvoteShare Job
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The Staff Analytical Scientist will be part of a team involved in DNA/RNA analysis, sample preparation, method development, data analysis, and instrument development. The scientist will assess nucleic acid and protein pharmaceuticals in biological extracts using liquid chromatography (LC), and electrophoresis (CE.
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Performs RNA/DNA/Protein Isolation, RT-PCR, ELISA/Western Blot, Immunohistochemistry & Immunofluorescence. The candidate should be proficient in RNA/DNA/protein isolation, RT-PCR, western blot/ELISA.
ExpandApply NowActive JobUpdated 8 days ago - UpvoteDownvoteShare Job
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The laboratory uses a multi-disciplinary approach to understand protein/ RNA structure, interactions and function, including enzyme assays, spectroscopic methods, and structural studies using X-ray crystallography and cryo-EM. Research duties associated with this post will include DNA manipulation, bacterial culture, and purification of recombinant proteins, and in vitro RNA transcripts.
ExpandApply NowActive JobUpdated 11 days ago - UpvoteDownvoteShare Job
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Relevant experience in general biological laboratory work (protein, DNA/RNA and cell-based techniques) is required. Develop and conduct state-of-the-art scientific experiments with mouse models of disease, initially with supervision and then progressively independent work, including:Conventional PCR and qPCR genotypingMouse colony managementImmunohistochemical approaches on mouse CNS tissueSurgical approaches, especially CNS-driven, on mice to study obesity and diabetesGlycemic and metabolic experiments in mice.
Full-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Strong background in basic research or translational research in oncology, including but not limited to high throughput screening, cell-based assays, protein biochemistry, molecular biology with emphasis on RNA technologies.
ExpandApply NowActive JobUpdated 7 days ago - UpvoteDownvoteShare Job
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Experience with molecular biology techniques such as DNA and RNA extraction, qPCR, protein quantification, ELISA, and enzymatic assays is required. superfamily of cell proteins and named for the visual resemblance of a scholar rock to protein structures, the clinical-stage company is focused on advancing innovative treatments where protein growth factors are fundamental.
ExpandApply NowActive JobUpdated 11 days ago
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