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Demonstrated experience with routine molecular biology techniques (DNA/RNA/protein isolation, cDNA synthesis, RT-PCR, qPCR, digital PCR, western blot, and immunofluorescence) + Perform DNA, RNA, and protein isolation from mammalian cells.
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Develop and implement algorithms across a range of in-house acquired data including, but not limited to genetic sequences, RNA expression, protein expression and protein structure.
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ResponsibilitiesExtract protein, DNA and/or RNA from necropsied animal tissueRun ddPCR, qPCR, ELISA, Western Blot etc analysis on tissue extractsCell culture, Neutralizing antibody assays and total antibody assaysSample analysis assay optimizationSOP writingData recording and analysisQC analysis This position directly impacts preclinical outcomes including proof of concept, ED50, MED, clinical hold response and IND enabling studies.
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A qualified candidate will assist in experimental research tasks using standard molecular biology techniques (DNA/RNA extractions, PCR, cloning, DNA/protein quantification, DNA and SDS PAGE electrophoresis.
ExpandApply NowActive JobUpdated 11 days ago - UpvoteDownvoteShare Job
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Strong background in basic research or translational research in oncology, including but not limited to high throughput screening, cell-based assays, protein biochemistry, molecular biology with emphasis on RNA technologies.
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Experience must be in cell/molecular biology, RNA modulation, protein translation research in Oncology. Experience in research involving RNA and protein translation desired, but not required.
Full-timeExpandApply NowActive JobUpdated 3 days ago - UpvoteDownvoteShare Job
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Broad experience and expertise in molecular reagent generation and cell line engineering using gene editing approaches CRISPR as well as development and implementation of novel cellular target engagement activity and PPI assays e.g. immunoassays second messenger generation ion flux reporter protein stability PPI splitNanoLuc split-gal gene activation cellular imaging.
ExpandApply NowActive JobUpdated 21 days ago - UpvoteDownvoteShare Job
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Proven hands-on experience and knowledge with routine molecular biology techniques (DNA/RNA/protein isolation, cDNA synthesis, RT-PCR, qPCR, digital PCR, western blot, and immunofluorescence.
Full-timeExpandApply NowActive JobUpdated 30 days ago - UpvoteDownvoteShare Job
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Performing protein quantification assays and multi-parameter flow cytometry. Next-generation DNA and RNA sequencing. The UCSF lung transplant research lab is seeking a specialist-series with experience in immunology or molecular biology to participate in several exciting ongoing projects.
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To realize this vision, we are building therapeutics that modify and control multiple genes at the DNA, RNA, and protein level in vivo. A Ph. D. in pharmacology, physiology, drug delivery, genetics or a related life sciences discipline, with >5 years of drug development experience leading preclinical assay development efforts.
Full-timeExpandApply NowActive JobUpdated 25 days ago - UpvoteDownvoteShare Job
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As a Product Designer for Modified Biologics, you will partner with our talented team delivering solutions for scientists using breakthrough techniques in DNA, RNA, protein and antibody design and analysis to drive science forward.
$159,885 - $216,315 a yearFull-timeExpandApply NowActive JobUpdated 10 days ago - UpvoteDownvoteShare Job
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Familiarity with protein engineering techniques and their applications in therapeutic development, particularly in the context of lipid nanoparticle-based delivery systems. Stay abreast of the latest advancements in lipid nanoparticle technology, RNA/DNA therapeutics, and relevant scientific literature to inform decision-making and maintain a competitive edge.
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Candidates will perform molecular biology techniques, particularly cloning targeting constructs and CRISPR plasmids; will assist in culturing cancer cells and stem cells; and will analyze RNA and protein expression via qPCR analysis, immunofluorescence, and Western blot.
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