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This position is based in San Diego, CA. Depending on experience, the scientist will expand molecular and product specific assay development working with the Gene Therapy Research and Development team.
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The Molecular Assay Development team is seeking an accomplished (Senior) Scientist to join our team within the Cellular Therapy Analytical Development (CTAD) organization. Expert knowledge of and hands-on experience developing and optimizing analytical methods using molecular biology techniques, including various PCR-based methods and/or next-generation sequencing.
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Develop and perform experiments supporting research and development including assay development for PCR and sequencing and method development of various sample collection and extraction methods.
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Biology techniques (Protein, DNA and RNA isolations, Western blot, qRT-PCR, Flow Cytometry) transductions, RNA and protein preparation from cells and tissue, RT-PCR, western blotting, and ELISA.
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Expertise in virology, with skills in viral analytics (plaque assay, TCID50, indirect fluorescence assay), virus cultivation and propagation, as well as the design, rescue, and characterization of negative-sense single-stranded RNA viruses.
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Molecular biology techniques: DNA/RNA extraction, gene expression analysis (PCR/RTPCR), western blotting, ELISA, Next Generation Sequencing. 3-5 years of experience performing cell biology techniques: Mammalian cell culture, in vitro cellular assays (cell viability assay, proliferation, invasion, apoptosis), luciferase assay.
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We are seeking a highly motivated and talented scientist with background in cellular and molecular biology and assay development to join the Biotherapeutics and Genetic Medicine organization to support in vitro pharmacology work related to Genetic medicine research on AAV.
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1-2 years of hands-on Digital Droplet PCR assay design and analytical validation experience. For over 50 years, we have been partnering with healthcare and life science laboratories, manufacturers, and suppliers across the globe to co-create and provide biological control materials, assay services and consulting for microbiology, molecular diagnostics, and virology.
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The incumbent will be responsible for drug screening, cell-based assay development, and biomarker discovery. transductions, RNA and protein preparation from cells and tissue, RT-PCR, western blotting, and.
ExpandApply NowActive JobUpdated 24 days ago - UpvoteDownvoteShare Job
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Nuclein is an Austin-based, private equity funded, medical device company that offers an innovative, FDA EUA authorized, rapid PCR, point-of-care system. The individual will collaborate closely with Engineering team members, in addition to cross-functional teams including Assay Development, Customer Support, and Operations, to create innovative solutions and maintain product effectiveness.
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Job Title: Research & Marketing Intern – Assay Development. The Research & Marketing Intern will have a hybrid role, assisting with R&D projects and marketing content generation for the Assay Development group.
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Lead preclinical pharmacology including in vitro and in vivo assay development and execution across the organization. Experience with molecular biology including cloning, DNA sequencing, PCR, mutagenesis, transient and stable gene expression.
Full-timeExpandApply NowActive JobUpdated 17 days ago - UpvoteDownvoteShare Job
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Working knowledge of skills in PCR methods, LCMS, Flow cytometry are highly desirable. Expertise in Ligand Binding Assay Methods (ELISA, MSD, Gyrolabs, Simoa etc.) Strong knowledge of Bioanalytical Assay Validation regulations (FDA, EMA guidance.
Full-timeExpandApply NowActive JobUpdated 10 days ago - UpvoteDownvoteShare Job
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Perform recombinant DNA activities, ranging from cloning (Gibson Assembly, PCR, Vector Digestion) and DNA plasmid purification (small & large-scale) and in vitro transcription to generate assay controls.
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Experience in ELISA and PCR assay development is highly desirable. Experience running ELISA and PCR tests is essential; experience with related tests (e.g. Luminex IFA) would also be useful.
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