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Micro- Aseptic techniques, cell culture, cell plating and staining / Molecular- Assays, blotting, PCR, imaging). Strong knowledge and hands-on experience in cell biology and biochemical assays such as cell culture, ELISA and Western-blot.
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Conduct a wide range of biochemistry, molecular and cellular biology techniques to express, purify and characterize drug candidates (e.g. DNA/RNA isolation, plasmid construction, PCR, Octet, HPLC, mammalian cell culture, transient and stable transfections.
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The Cell Culture Development organization within Operations leads the process development and tech transfer of cell culture processes for clinical manufacturing and commercialization of therapeutic proteins in the AbbVie pipeline.
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Perform in vitro assays to evaluate efficacy of drug candidates (e.g. ELISA, flow cytometry, cell proliferation, anti-microbial assays). Perform in vitro assays to evaluate efficacy of drug candidates (e.g. ELISA, flow cytometry, cell proliferation, anti-microbial assays.
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Working knowledge on protein purification and hands-on experience on chromatography workstations preferred. The ideal candidate will function in a cutting-edge laboratory environment as part of a multi-disciplinary team of protein engineers, immunologists, molecular biologists, and protein biochemists to discover novel therapeutics with opportunity to develop cGMP or GLP compliant skills in an industrial laboratory setting.
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We are seeking a highly motivated and talented scientist with background in cellular and molecular biology and assay development to join the Company’s Biotherapeutics and Genetic Medicine organization to support in vitro pharmacology work related to Genetic medicine research on AAV.
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Knowledge and direct experience with various human cell culture platforms, especially in human pluripotent stem cell culture and differentiation processes towards products for regenerative medicine.
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May perform stem cell culture and differentiation, process optimization and/or scale up to improve GMP production efficiency. Able to develop, revise, and review protocols or SOPs, batch records, cell culture process development and technical reports.
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Support early & late-stage CMC development activities including cell line development (CLD), cell culture development (CCD), & purification development for product quantitation, product quality & process impurities for biologic molecules.
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Conducting design review including specifications, procurement, fabrication management, and installation of equipment, facilities, and utilities related to the manufacture of biologics bulk drug substance including basic unit operations involving fermentation, cell culture and protein purification and related equipment.
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Other benefits include medical, dental, vision, health savings account, unlimited vacation, car allowance, cell phone allowance, 401k, innovative purpose-driven colleagues to learn from and enjoy, and a great culture rooted on our core values - Unity, Excellence, Drive, Compassion, and Fun.
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Assist in the development and application of molecular and cell-based assays (e.g., qPCR, ddPCR, ELISA, SDS-PAGE, WB, Endotoxin assay) Understand and enforce company culture, teamwork, safety, appropriate handling of materials in an BSL2 environment.
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Develops, optimizes, characterizes and troubleshoots cell culture processes to produce mAbs, gene therapy vectors, and other biologics. Develops new cell culture growth and feed media formulations.
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Proactively communicate with colleagues, third-party partners, and customers as needed using remote/virtual tools such as cellular phone, WebEx, Microsoft Teams, and other similar tools. LG Energy Solution develops and manufactures lithium ion polymer batteries and packs for electric vehicle (EV) and energy storage applications.
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Prior knowledge of Cell and Gene Therapy clinical modalities, biopharmaceutical manufacturing, process development, and GMP. Drive partnership with Genomic Medicine Account Management teams, Field Application Scientists and other OpCos to identify opportunities and to drive Design-In of Cytiva Cell Therapy products specified in customers’ early-stage drug development process.
$180,000 - $200,000 a yearFull-timeExpandApply NowActive JobUpdated 1 month ago
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