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Extensive hands-on experience with standard immunological techniques including multi-parameter flow cytometry, cell sorting, immunoassays such as ELISA, Cytotoxicity, in vitro co-culture assays (MLR, PBMC cultures, etc), and reporter bioassay development.
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Expertise in primary human cell culture, multi-color flow cytometry, multiplex cytokine detection, functional immune cell assays (proliferation, cytotoxicity, chemotaxis) and assay development is essential.
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You have experience with primary human immune cell activation assays using multparameter flow cytometry. You have experience with T cell cytotoxicity assays using endpoint flow cytometry measurements.
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Develop and validate immunological assays (, flow cytometry, ELISA, CyTOF, cytokine profiling) to evaluate drug candidates' efficacy and mechanism of action. Learn more about Flagship at Position Overview:We are seeking a highly skilled PhD level Principal Scientist with proven experience in immunology and preclinical research to join our team.
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Expertise in cell culture, PCR, ELISA, western blot, and flow cytometry. The successful candidate will join a dynamic, multi-disciplinary team and play a key role in developing and applying in vivo models to evaluate novel cancer therapies in the early-stage drug discovery pipeline.
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The ideal candidate will have neuroscience research experience employing a variety of in vitro/in vivo electrophysiology techniques including traditional whole-cell patch-clamp, extracellular field potential recordings, and qEEG. Additional computational or programming experience is also required.
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Experience in flow cytometry, microbiology, PCR and ELISA testing is a plus. Demonstrate basic knowledge of the GXP cellular therapy product manufacturing, and program development and evaluation, as well as needs assessment and marketing of the programWorking knowledge of flow cytometry, molecular biology, and genetic engineering is a plus.
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Hands-on experience in tissue culture, plate-based assays, RNA isolation, gene expression analysis (qPCR), western blot, ELISA, multiplex protein analysis, flow cytometry preferred. Experience with hands on and/or managing in vivo work at CROs is a plus.
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Expertise in at least one of the following assay methods: ELISA, Western blot, qPCR, flow cytometry, ChIP. Implement target-specific assays to assess target and drug activity in vitro and/or in vivo, as appropriate.
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Experience with cell and gene therapy test methodologies (qPCR/ddPCR, Flow Cytometry, ELISA, and cell-based assays). The QC Associate will support cellular therapy product release testing within the QC analytical laboratory at our BaseCamp facility in Waltham.
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Nanoparticles, or similar, and in vivo models is desirable. Experience with LNP formulations and in vivo study execution is a. ● Contribute to LNP formulations and in vivo studies in relevant models.
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Your hands on experience with cell-based assays (e.g., cell-binding, proliferation, cytotoxicity, apoptosis, receptor activation, internalization, cytokine secretion, immune cell activity, gene expression response) for antibody and biologics screening and characterization (reporter cells, primary cells) using a variety of techniques (e.g., flow cytometry, luminescence, fluorescence, cell imaging) is needed.
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Experience with mammalian cell culture and established molecular and biochemical techniques including flow cytometry, fluorescence microscopy, cell reporter systems, cloning, qPCR, western blot, and ELISA.
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Under the general supervision of the investigator, performs complex laboratory experiments in the field of cell biology including: cell culture, ELISA, DNA/RNA isolation, PCR, general biochemistry, immunohistochemistry, flow cytometry, and microscopy.
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Strong knowledge of biomarker technologies and methodologies, including genomics, proteomics, imaging, and flow cytometry, as applied to clinical research. Senior Scientist, Clinical Biomarkers 142424 Posted: 01th April 2024 140000 USD - 180000 USD Boston , United States Permanent Job Title: Principal Scientist, Clinical Biomarker Company Overview: Join a dynamic and forward-thinking mid-sized biotech company dedicated to advancing breakthrough therapies and diagnostics in the field of life sciences.
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vivo flow cytometry associate scientist jobs in Watertown, MA
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