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Extensive hands-on experience with standard immunological techniques including multi-parameter flow cytometry, cell sorting, immunoassays such as ELISA, Cytotoxicity, in vitro co-culture assays (MLR, PBMC cultures, etc), and reporter bioassay development.
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Expertise in primary human cell culture, multi-color flow cytometry, multiplex cytokine detection, functional immune cell assays (proliferation, cytotoxicity, chemotaxis) and assay development is essential.
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You have experience with primary human immune cell activation assays using multparameter flow cytometry. You have experience with T cell cytotoxicity assays using endpoint flow cytometry measurements.
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Expertise in cell culture, PCR, ELISA, western blot, and flow cytometry. The successful candidate will join a dynamic, multi-disciplinary team and play a key role in developing and applying in vivo models to evaluate novel cancer therapies in the early-stage drug discovery pipeline.
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Expertise in at least one of the following assay methods: ELISA, Western blot, qPCR, flow cytometry, ChIP. Implement target-specific assays to assess target and drug activity in vitro and/or in vivo, as appropriate.
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Develop and validate immunological assays (, flow cytometry, ELISA, CyTOF, cytokine profiling) to evaluate drug candidates' efficacy and mechanism of action. Learn more about Flagship at Position Overview:We are seeking a highly skilled PhD level Principal Scientist with proven experience in immunology and preclinical research to join our team.
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The ideal candidate will have neuroscience research experience employing a variety of in vitro/in vivo electrophysiology techniques including traditional whole-cell patch-clamp, extracellular field potential recordings, and qEEG. Additional computational or programming experience is also required.
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Experience in flow cytometry, microbiology, PCR and ELISA testing is a plus. Demonstrate basic knowledge of the GXP cellular therapy product manufacturing, and program development and evaluation, as well as needs assessment and marketing of the programWorking knowledge of flow cytometry, molecular biology, and genetic engineering is a plus.
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Hands-on experience in tissue culture, plate-based assays, RNA isolation, gene expression analysis (qPCR), western blot, ELISA, multiplex protein analysis, flow cytometry preferred. Experience with hands on and/or managing in vivo work at CROs is a plus.
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We are seeking a highly motivated Principal Associate Scientist with experience in cellular and molecular biology techniques for drug discovery. Proficiency in a broad range of biochemical, molecular and cellular techniques including (but not limited to): mammalian cell culture, western blotting, qPCR, transfection, flow cytometry etc.
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Broad technical expertise/knowledge including with flow cytometry, ELISA, immunohistochemistry, qRT-PCR, NGS and RNA Seq. Broad technical expertise/knowledge including with flow cytometry, ELISA, immunohistochemistry, qRT-PCR, NGS and RNA Seq.
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Experience with cell and gene therapy test methodologies (qPCR/ddPCR, Flow Cytometry, ELISA, and cell-based assays). The QC Associate will support cellular therapy product release testing within the QC analytical laboratory at our BaseCamp facility in Waltham.
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Nanoparticles, or similar, and in vivo models is desirable. Experience with LNP formulations and in vivo study execution is a. ● Contribute to LNP formulations and in vivo studies in relevant models.
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Performing in vivo catheterizations for measurement of vascular and chamber pressure in cardiovascular rodent models. Communicating, collaborating and consulting with veterinarians, peers and scientific investigators on best practice, optimization and production of in vivo, surgical models.
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Under the general supervision of the investigator, performs complex laboratory experiments in the field of cell biology including: cell culture, ELISA, DNA/RNA isolation, PCR, general biochemistry, immunohistochemistry, flow cytometry, and microscopy.
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vivo flow cytometry associate scientist jobs in Boston, MA
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