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This is a small molecule & radiopharmaceutical focus analytical development role supporting new and improved analytical methods and commercial processes, physico/radiochemical characterizations in support of late phase pharmaceutical development, technology transfer to Contract Manufacturing Organizations (CMO), and authoring CMC non-clinical dossier sections.
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Representing the Analytical Development team in cross-functional meetings, presenting results and providing scientific input as needed. Scientist I, gRNA Analytical Development. RNA or Oligonucleotide analytical chemistry and biophysical techniques (required) , preferably in biopharmaceutically relevant systems.
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This position will execute the development of novel active pharmaceutical ingredients (API) within the immuno-oncology biologics pipeline from the early Process Development stage through GMP production (Clinical Phase 1-3.
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Responsible for overseeing the development/validation/sample analysis for mass spectrometry assays for pharmacokinetic and immunogenicity bioanalysis for all therapeutic modalities (proteins, mono, bi and tri-specific molecules, gene therapy, cell therapy, radioligand therapeutics and more.
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The successful candidate will be pursuing an undergraduate degree in Electrical Engineering, Computer Science, Mathematics, Physics or a related field with hands-on experience in one or more of the following areas: software development, graphical user interface development, real time software, MATLAB or C.
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2+ years of hands-on experience with development and implementation of state-of-art multiplex immuno analytics, e.g. ELISA, Octet, Biacore, Luminex and MSD for complex protein or biologics based drug substance characterization.
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Manage development of in vitro and in vivo models to enable new target selection and characterization, and biomarker identification. Laboratory research/Assay development/Automation. A subject matter expert in Immunology, automation and assay development.
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The ElevateBio ecosystem combines multiple R&D technology platforms – including Life Edit, a next-generation, full-spectrum gene editing platform; comprehensive cell engineering technologies; and an expanded viral and non-viral therapeutic delivery platform – with BaseCamp®, its end-to-end genetic medicine cGMP manufacturing and process development business, to accelerate the discovery and development of advanced therapeutics.
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PEDIATRIC PHYSICAL THERAPIST / AMBULATORY CARE / CENTER FOR CHILD DEVELOPMENT/ BWH BOSTON MA TEMPORARY/ Benefits Eligible! Posted job title: Pediatric Physical Therapist/ Ambulatory/ Center For Child Development.
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Experience with programming in Python, full-stack software development, good documentation practices, version control and collaboration with git, environment management (e.g., poetry, conda, docker), DevOps tooling (e.g., Infrastructure as Code, Github Actions, Kubernetes), and ML/LLMOps tooling (e.g., MLFlow, LangFuse.
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You are excited about leading the development of innovative CMC regulatory strategies and the preparation and submission of high‐quality CMC sections of INDs and CTAs, in close collaboration with regulatory team members, our in‐house CMC and Quality teams, contract manufacturing organizations, external experts and global health authorities.
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This is a senior-level position that requires a deep understanding of the financial markets, exceptional networking skills, and a strong background in commercial real estate development. Coordinate and manage regional & international travel arrangements for investor presentations with WS Development senior leadership.
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Manage cell line development, clone selection/stability, upstream/downstream development and manufacturing operations at the CDMOs∯*∯ In this role, the ideal candidate will be responsible for overseeing cell line and process development, tech transfer, scale-up and DS manufacturing at the CDMOs∯*∯ You will collaborate with groups like analytical, formulation and QC to assist method development, reference standard characterization, release and stability studies.
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Expertise in primary human cell culture, multi-color flow cytometry, multiplex cytokine detection, functional immune cell assays (proliferation, cytotoxicity, chemotaxis) and assay development is essential.
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Position Description:The Neurophysiology Group within the Research and Development organization is searching for an experienced electrophysiologist to support novel drug discovery research in CNS disorders.
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development job Title: computer in Lexington, MA
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