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Extensive experience in flow cytometry, as well as molecular and cellular biology; Develop and execute efficient strategies for target identification, prioritization and validation; review, propose, initiate, and implement new pre-clinical therapeutic antibody drug discovery and development programs in the field of Immunology and Inflammation.
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Expertise in biomarker discovery and development, including proficiency in molecular and cellular techniques, genomics, and bioinformatics. The successful candidate will play a pivotal role in advancing the pipeline from preclinical stages through clinical development, leveraging their expertise in translational medicine, biomarker development, and oncology/immunology.
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Leading a cross functional team for a) the identification of new indications for Alexion therapeutics; b) the functional differentiation of Alexion targets from competitors; c) driving rigorous translational understanding of clinical trial data, d) drive key translational/BM hypothesis for treatment response or non-responsiveness e) lead efforts to drive translational research strategy for the different programs in nephrology TA.
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A minimum of a Bachelors degree Biology, Molecular and Cellular Biology, Pharmacology, Immunology or related scientific discipline. This is an exciting opportunity to join the Oncology Translational Research (OTR) department at Novartis Biomedical Research in Cambridge, MA. OTR is a global laboratory-based research group, which supports the development of novel therapeutics in the Oncology Disease Area from early stages of target identification through proof-of-concept clinical trials.
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Implement clinical biomarkers and ensure biomarker-driven decision-making across all phases of drug development. We are passionate about delivering on the promise of cellular and gene therapy, shaping the future of cellular medicine, and delivering new therapies to millions of patients with treatment options.
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Clinical research in Dr. Hamrah’s laboratory is focused on using live imaging - in vivo confocal microscopy - to better understand molecular and cellular mechanisms in corneal immunology, neuro-immunology and inflammation.
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Visterra, Inc., is seeking a highly motivated Research Associate with research experience in biochemistry, cellular and/or molecular biology to help discover and develop biologic therapeutics, as well as expand platform technologies that support our antibody-based drug discovery programs.
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And cellular therapy (stem cell) laboratory. 7+ years experience in clinical blood bank laboratory in all areas (processing, testing, storage, release, etc.) Current certification as Medical Technologist, Medical Laboratory Scientist, or similar; ASCP certification strongly preferred.
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Requires significant experience in biopharmaceutical industry and strong understanding of all aspects of biopharmaceutical drug development, including clinical, nonclinical, regulatory, CMC, and commercial.
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Provide 24-hour supervision of daily clinical and administrative operations for our 14 bed Inpatient Stem Cell Transplant (SCT) unit, treating infants to young adults undergoing stem cell transplant for malignant and non-malignant diseases.
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Performs routine laboratory procedures, i.e. DNA cloning, transfection, cell culture, PCR, agarose gel electrophoresis, immunoassays such as ELISA, cellular staining, etc. The Center for Virology and Vaccine Research (CVVR) at Beth Israel Deaconess Medical Center aims to promote research and education activities related to virology, vaccinology, and related disciplines, including basic, translational, and clinical vaccine research.
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Experience in blood collection, therapeutic and cellular therapies, and infusion. Knowledge of clinical trial methodology, regulatory and compliance requirements governing clinical trials and experience in the development of clinical strategy and the design of study protocols.
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We have conducted the first successful OTOF gene therapy clinical trial in children born with complete hearing loss, with the restoration of hearing and speech capability (Lv et al., The Lancet, 2024.
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Independently design and execute on cellular assay strategy to support indication selection and expansion of lead optimization program. Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients' lives.
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The position represents a key partner in establishing and driving forward tactical plans to enable Editas to deliver on its mission to translate the power and potential of genome editing into a broad class of in-vivo and cellular treatments that transform lives of people living with serious diseases.
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cellular clinical jobs in Cambridge, MA
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