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Overview Sr. Research Technician - CAR T cell Pre-clinical lab developing next generation cellular immunotherapies focused on CAR T cell immunotherapy for cancer is looking for an exceptionally motivated individual with past lab experience to join the lab team of Dr. Eric Smith, Director of Translational Research, Immune Effector Cell Therapies at Dana Farber.
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Collaborate with a world class, multidisciplinary team of drug discovery scientists from medicinal and platform chemistry, DEL, in vitro pharmacology, biology, and data science to advance multiple small molecule programs as new clinical candidates for the treatment of several diseases.
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Building on the company's leadership in the field of cellular metabolism, Agios is advancing a robust clinical pipeline of investigational medicines with active and planned programs in alpha- and beta-thalassemia, sickle cell disease, pediatric PK deficiency and MDS-associated anemia.
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Responsible for all quality aspects in collection of cellular products to support clinical trials (INDs) and external study sponsors. Reviews SOPs, policies, change controls, corrective and preventative action plans, and engraftment/outcome data related to clinical trials and investigational products along with the research RN and compliance officer.
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Test methods include, but are not limited to molecular (SSO, SSP, SBT, NGS) and serologic typing, flow cytometry, cellular methods and complement dependent cytotoxicity. Oversee execution of high quality, reliable and cost-effective clinical HLA testing services.
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This is an excellent opportunity for early career clinical pathologists with experience in blood banking, apheresis, and cellular therapy. The applicant will report to the current Blood Bank Medical Director and share clinical service coverage as well as educational responsibilities, including didactics and service-related teaching for pathology and laboratory medicine residents, and interdepartmental teaching of Medical School students and residents (e.g., general medicine, nephrology, hematology/oncology, surgery, dental, etc.
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Working independently, under the general supervision of senior personnel, the Research Associate will perform highly specialized experimental procedures involving in vitro protocols, advanced molecular genetics, and cellular biology techniques.
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Performs routine laboratory procedures, i.e. DNA cloning, transfection, cell culture, PCR, agarose gel electrophoresis, immunoassays such as ELISA, cellular staining, etc. The Center for Virology and Vaccine Research (CVVR) at Beth Israel Deaconess Medical Center aims to promote research and education activities related to virology, vaccinology, and related disciplines, including basic, translational, and clinical vaccine research.
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We are passionate about delivering on the promise of cellular and gene therapy, shaping the future of cellular medicine, and delivering new therapies to millions of patients with treatment options.
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Major in Biochemistry, Biophysics, Pharmacology, Molecular/Cellular/Chemical Biology, or a related field. The company has a portfolio of proprietary commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia and bipolar I disorder, and a pipeline of clinical and preclinical candidates in development for neurological disorders.
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And cellular therapy (stem cell) laboratory. Skills: 7+ years‘experience in clinical blood bank laboratory in all areas (processing, testing, storage, release, etc.) Current certification as Medical Technologist, Medical Laboratory Scientist, or similar; ASCP certification strongly preferred (not required, equivalent experience would be considered.
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Responsible for all quality aspects in collection of cellular products to support clinical trials (INDs) conducted at BWH, Dana-Farber Cancer Institute, and external study sponsors. The incumbent is responsible for coordinating all quality activities in Apheresis to support all clinical trials involving investigational cell therapy products.
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RASyn is seeking an innovative, self-motivated, and team-oriented Scientist in Protein Engineering, with a passion for developing assays to support the interrogation of protein libraries using a variety of display, cellular, and molecular techniques.
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In this role, the scientist will utilize cellular assays to support our hit ID and lead optimization efforts and bring innovative ideas in assay development and lab-based leadership. We are using models early to fail less often, executing clinical trials to add valuation to the company, and generating fit-for-purpose data to feed back into Valo’s Opal Computational Platform as we reinvent drug discovery and development from the ground up.
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A key focus will be the development and application of novel rare variant methods that combine results from large-scale DNA sequencing data sets with experimental perturbation within in vitro cellular models, ultimately to infer the mechanistic effects of disease-associated variants.
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cellular clinical jobs in Waltham, MA
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