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Experience with in vivo nucleic acid delivery (hydrodynamic, viral vectors, lipid nanoparticles. NewLimit is seeking an scientist with in vivo physiology experience to contribute to our Metabolism and Immunology programs.
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Extensive in vivo skillset is required, including tumor inoculation and measurement (BLI imaging, caliper), animal dosing (i.v., i.p., and s.c.), blood/tissue collection and ex vivo analysis.
$80,000 - $105,000 a yearExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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This role spans the oversight of guideRNA synthesis, medicinal and linker chemistry, orchestrating a team that's both in-house, CROs, and FTEs. You're not just part of the strategy; you're the visionary behind it, sculpting the path our gene editing platform will take to achieve efficient in vivo efforts.
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Broad and extensive expertise with all aspects of in vivo science (various dosing routes, anesthesia, surgical procedures, necropsy, tissue processing, etc.) The role of In Vivo Hub Research Associate is pivotal in providing comprehensive support to core operations and directly reporting to the In Vivo Hub Manager.
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The In Vivo Pathology (IVP) team within the Pathobiology department is seeking a research associate to contribute to histology and pathology workflows in support of pre-clinical in vivo pharmacology studies.
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As the Associate Director you will play a pivotal role in establishing and expanding the company's capabilities for preclinical in vitro and clinical ex vivo disease pathobiology.
$170,000 - $200,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Lead preclinical pharmacology including in vitro and in vivo assay development and execution across the organization. 7+ years of relevant post-degree work experience in the pharmaceutical industry.
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In vitro work includes a range of cellular assays, cell culture including multiparametric flow cytometry and molecular biology techniques to help interpret in vivo observations. Data collection, analysis and reporting in vivo and in vitro studies.
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We are seeking a highly motivated Senior Principal Scientist/Associate Director specialized in characterizing the in vitro and in vivo ADME/PK properties of small molecule lead compounds and drug candidates.
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The successful candidate will be proficient in murine handling techniques including IV, IP, PO, SC, in-life and terminal blood collection, and handling of tissues during necropsy and processing for ex vivo analysis.
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The successful candidate will be responsible for the design, execution, and interpretation of mid/high throughput in vitro/ex vivo assays and mechanistic experimentation to advance early drug discovery projects from target concept through lead optimization.
$146,800 - $231,100Full-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Founded by CRISPR pioneer and Nobel laureate Jennifer Doudna and Trevor Martin, Janice Chen, and Lucas Harrington, the company’s ultracompact proteins are designed to enable in vivo gene editing in difficult to reach tissues utilizing both nuclease applications and new editing modalities beyond double stranded breaks, including base editing, gene writing, and epigenetic editing.
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Hands on experience with in vivo pharmacology model workflows. This position will support drug development in diverse therapeutic areas such as inflammation, fibrosis, oncology, and virology.
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Strong hands-on experience in designing and executing in vitro and in vivo studies to validate targets and treatment ideas using ADCs, mAbs, or other targeted therapies. ● Design and manage in vivo studies at CROs that will inform clinical dosing.
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Provide interpretation of in vitro, ex vivo and in vivo data that are generated both internally and with CROs; review and interpret bioanalytical data and reports; establish exposure-response relationships.
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in vivo jobs Title: post doctoral fellow Company: Emory University in South San Francisco, CA
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