Firefly Bio

The SVP/VP, Head of Biology will propose novel treatment ideas and develop a plan for drug discovery.. ● Establish strong in-house capabilities to perform in vitro experiments with high throughput and characterize the MoA of innovative payloads. ● Design and manage in vivo studies at CROs that will inform clinical dosing. ● Strong hands-on experience in designing and executing in vitro and in vivo studies to validate targets and treatment ideas using ADCs, mAbs, or other targeted therapies. ● Experience in IHC and/or proteomics

biology

About Firefly Bio:Firefly Bio is a Bay Area venture-backed company. Our mission is to unlock the full potential of bioconjugates and develop medicines with long-lasting benefits for patients. We are establishing an expert team to build state-of-the-art platform capabilities for the invention and development of innovative drug conjugates. Our company culture is built on the values of Focus, Integrity, Respect and Energy. We are looking for passionate individuals committed to making an impact on the future of medicine.Position Summary:The SVP/VP, Head of Biology will be instrumental in defining Firefly Bio’s strategy and target indications. The SVP/VP, Head of Biology will propose novel treatment ideas and develop a plan for drug discovery. The SVP/VP, Head of Biology will be a key leader in the organization and will build and oversee a team of biologists evaluating novel drug conjugates for applications in oncology and other areas of unmet medical need. Title and compensation package will be based on prior experience.Responsibilities:● Build an effective Biology team and oversee the functional characterization of bioconjugates● Propose novel drug conjugate targets and treatment ideas● Establish in-house capabilities to evaluate target expression on and in cells and in tissues● Establish strong in-house capabilities to perform in vitro experiments with high throughput and characterize the MoA of innovative payloads● Design and manage in vivo studies at CROs that will inform clinical dosing● Co-lead/lead drug discovery projects and assist in preparing documents to support IND filings● Participate in project teams and actively participate in the development of an innovative product portfolio● Advise company leadership and participate in Research leadership team meetings● Manage, mentor and develop staff to ensure Biology organization will effectively drive advancement of portfolio projectsRequirements and Experience:● Ph.D. in cancer biology, immunology or related discipline● 12+ years of work experience in a research and/or development environment and 6+ years of successful management/leadership● Strong experience in initiating and leading of drug discovery projects including IND submissions● Strong hands-on experience in designing and executing in vitro and in vivo studies to validate targets and treatment ideas using ADCs, mAbs, or other targeted therapies● Strong background in cancer biology and drug discovery including managing experiments at CROs● Skilled in bioinformatic tools for target and disease validation● Demonstrated strong leadership qualities as manager of a core function and as project team leader● Creativity and problem-solving skills paired with ability to excel in a highly collaborative environment● Excellent oral and written communication and interpersonal skills● Experience in IHC and/or proteomicsBenefits:Every team member is essential in shaping Firefly Bio’s culture and science and for our success. We offer competitive compensation packages including stock options and the opportunity to be part of ground-breaking research. Firefly Bio is an equal opportunity employer and will consider all applicants for employment. Firefly Bio does not discriminate on the basis of race, sex, color, religion, age, national origin, marital status, disability, veteran status, genetic information, sexual orientation, gender identity or any other reason prohibited by law in provision of employment opportunities and benefits.

START NEW SEARCH