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We have built a deep portfolio of AVV-based gene therapy product candidates, with five product candidates in clinical trials: 4D-150 for the treatment of wet age-related macular degeneration (wet AMD) and diabetic macular edema (DME), 4D-710 for the treatment of cystic fibrosis lung disease, 4D-310 for the treatment of Fabry disease cardiomyopathy, 4D-125 for the treatment of X-linked retinitis pigmentosa (XLRP), and 4D-110 for the treatment of choroideremia.
ExpandApply NowActive JobUpdated 16 days ago - UpvoteDownvoteShare Job
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In terms of viral vector service, GenScript ProBio has a stable and high-yield viral vector platform. In terms of plasmid service, GenScript ProBio supports the most clinical approvals for CGT drugs including mRNA vaccines, CAR-T in China.
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The candidate's main responsibilities will include: a) novel assay development, b) in-vitro T cell circuit design and validation, c) establishment of in-vivo tumor models, d) compiling pre-clinical results to support the designation of clinical vector design, and e) leading the in-vitro and in-vivo pharmacology characterization of therapeutic product candidates in collaboration with a process development team towards an IND filling.
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We seek to unlock the full potential of gene therapy using our platform, Therapeutic Vector Evolution (TVE), which combines the power of directed evolution with our approximately one billion synthetic AAV capsid-derived sequences to invent evolved vectors for use in our products.
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Reporting to the Senior Manager of ADQC, the primary role of the Scientist I in Analytical Development/Quality Control (ADQC) is to provide support to clinical programs by providing quality testing and delivering results in accordance with cGMP standards.
$128,000 - $149,000 a yearFull-timeExpandApply NowActive JobUpdated 2 months ago - UpvoteDownvoteShare Job
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The Sr. Research Associate will support the Discovery Bioscience team and assist in developing and executing screening assays for the evaluation of AAV vector products. Participate in sample management activities such as receiving, processing, storage, and shipping pre-clinical samples.
$86,300 - $115,000 a yearFull-timeExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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This is an excellent opportunity to learn cutting-edge engineered T cell cancer therapy from leading experts in the field and gain highly sought after pre-clinical development experience in the field of cell therapy.
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