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Perform flow cytometry, ELISA, cellular cytotoxicity, qPCR, and other analytical assays to enable the characterization, release testing and stability monitoring of viral vector and cell therapy products and in-process samples.
$100,000 - $138,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our expert team collaborates closely with MD Anderson’s research and clinical faculty, bringing impactful cell therapies to cancer patients.
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The drug product team is also investing in building new platforms to support complex formulations such as lipid nanoparticles, Antibody Drug Conjugates and AAV and other non-viral vector delivery.
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Adverum’s core capabilities include clinical development, novel vector discovery and in-house manufacturing expertise, specifically in scalable process development, assay development, and current Good Manufacturing Practices quality control.
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The Hearth is the home of a custom-designed cGMP facility dedicated to AAV viral vector manufacturing and will host end-to-end manufacturing services to accelerate gene therapy programs from preclinical through clinical and commercial stage manufacturing.
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We have built a deep portfolio of AVV-based gene therapy product candidates, with five product candidates in clinical trials: 4D-150 for the treatment of wet age-related macular degeneration (wet AMD) and diabetic macular edema (DME), 4D-710 for the treatment of cystic fibrosis lung disease, 4D-310 for the treatment of Fabry disease cardiomyopathy, 4D-125 for the treatment of X-linked retinitis pigmentosa (XLRP), and 4D-110 for the treatment of choroideremia.
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In terms of viral vector service, GenScript ProBio has a stable and high-yield viral vector platform. In terms of plasmid service, GenScript ProBio supports the most clinical approvals for CGT drugs including mRNA vaccines, CAR-T in China.
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GenScript ProBio's total cell and gene therapy solution covers CMC of plasmid and virus for IND filing as well as clinical manufacturing and commercial manufacturing. It is also the first GMP manufacturing platform to provide in vitro transcription (IVT) template linearized plasmids for mRNA vaccines and has supported several mRNA vaccine global enterprises to obtain clinical approvals.
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This position usually carries an appointment of 65-80% diagnostic service, including all routine services provided by the clinical pathology lab, such as interpretation of cytology, hematology, chemistry, and urine samples, and consultation with clinicians, house officers, and veterinary students.
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Adverum is a clinical-stage gene therapy company targeting unmet medical needs in ophthalmology and rare diseases. Adverum is a clinical-stage gene therapy company targeting unmet medical needs in ophthalmology and rare diseases.
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Our Vector Program group, including Manufacturing Sciences and Technology (MS&T), Analytical Sciences and Technology (AS&T) and External Manufacturing (EM) teams, provides Chemistry, Manufacturing and Controls (CMC) support for basic, translational and clinical research for adeno-associated virus (AAV) vector-based therapeutic products.
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Provide expertise for the scale-up, optimization and tech transfer, and validation, of upstream cell culture and viral vector unit operations to internal and external partners in support of clinical manufacturing of vaccine products.
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The Sr. Research Associate will support the Discovery Bioscience team and assist in developing and executing screening assays for the evaluation of AAV vector products. + Participate in sample management activities such as receiving, processing, storage, and shipping pre-clinical samples.
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With more than 55 locations globally, we provide our clients with coordinated, end-to-end capabilities through all phases of drug development, including API, biologics, viral vector services, formulation, clinical trial solutions, logistics services and commercial manufacturing.
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Gene Delivery Product and Analytical Development (GDPAD) leadership seeks applicants for the Product and Analytical Lead role to drive strategy, knowledge, and deliverables related to lentiviral, AAV vector analytics development that are required for CMC milestone achievement of clinical program.
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