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Are excellent in most of the following: bacterial culturing, PCR, gel electrophoresis, molecular cloning, plate reader assays, cell-free expression systems, protein purification, buffer and media preparation, and DNA purification, sequencing, and analysis.
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Work with relevant stakeholders to identify fermentation process requirements that enable effective downstream processing for product separation and purification. Senior Scientist / Engineer or Director of Fermentation.
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Familiarity with bench scale fermentation units (e.g. PALL, Sartorius, DASGIP, Applikon and New Brunswick Eppendorf) Setup, operating, and tear down of large scale fermentors including monitoring of in-process fermentation parameters.
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Research Associate, Protein Science, protein expression, purification, microbial cell culturing, molecular cloning, biochemical synthesis, FPLC, SDS-PAGE, ELISA, colorimetric assays, Microsoft Office.
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Expertise in fungal or microbial physiology, mycology/microbiology, fermentation, data science and statistics strongly desired, bioinformatics and genome editing experience is preferred. Expertise in fungal or microbial physiology, mycology/microbiology, fermentation, data science and statistics strongly desired, bioinformatics and genome editing experience is preferred.
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Lead purification process development for AAV gene therapy, mRNA and protein therapeutics. We are seeking a highly experienced Senior Scientist in purification process development and manufacturing to join the Technical Operations team within the Institute of Medicine.
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Must have at least 3 years of post-bachelor working experience in a Biotech, Pharma, or Academic lab with hands-on experience in protein purification using lab scale AKTA instruments, UNICORN software, and chromatographic resins.
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Required Qualifications: BS/BA and/or MS/MA in a related field and 2+ years of related experience Experience in tissue culture (especially induced pluripotent stem cells) Experience in molecular biology techniques (e.g. RNA/DNA purification, PCR, cloning, etc.
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6+ years of experience in process manufacturing environment in food, dairy, chocolate, fermentation and/or pharmaceutical facilities including either:Process engineering and design including creating H&M balances, process flow diagrams, scaling up process from pilot to commercial scales and/or,Project engineering including leading projects from concept through operations, equipment specification, installation, and commissioning.
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Experience with molecular cloning or protein expression and purification. Our goal is to leverage the physical and chemical properties of building blocks of life for useful applications in science and medicine, such as new scientific tools to aid in cryo-electron microscopy (cryo-EM) and to build a novel class of targeted therapeutics to treat complex diseases.
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Hands on experience with ADC chemistry, reaction processes and purification methods (i.e., Tangential flow filtration, chromatography, etc. Technical knowledge at design, execution and data interpretation of experiments related to development, optimization, and scale-up of biologics with a focus on ADC BioConjugation and Purification processes.
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Experience in protein expression, purification, and structural characterization techniques such as X-ray crystallography, cryo-EM, and computational modeling. Experience in protein expression, purification, and structural characterization techniques such as X-ray crystallography, cryo-EM, and computational modeling.
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Experience with boilers, air compressor systems, pumps, water purification systems such as reverse osmosis, vapor compression stills, clean steam generators, ancillary utility support systems and the automated controls that drive them is highly desired.
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Supervises the operation of automatic and manually controlled purification and water treatment equipment, including pumps, motors, chemical feeders and filters to control the quality and regulate the flow of water through a treatment plant; conducts water analysis under general supervision to maintain water quality and proper chemical dosage in filtration plant.
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Solid working knowledge of various manufacturing platforms (Microbial fermentation process, IB recovery and refolding, CHO cell culture and purification, Pegylation, PEGylated protein purification etc.
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fermentation purification jobs in Emeryville, CA
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