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Calibr-Skaggs supplements the discovery process with the required disciplines for drug development which include chemical library screening, medicinal chemistry, in-vivo model optimization, formulation development, pharmacokinetic and toxicologic expertise, and early clinical development.
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Demonstrate expert understanding of computational chemistry principles and their application within a multidisciplinary drug discovery environment. PhD degree in a Computational Chemistry with 10+ years experience in Pharma/Biotech.
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The Research Associate will be responsible for conducting hands-on experiments including but not limited to molecular biology, mammalian cell culture, recombinant protein purification and characterization.
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As a key member of their research and development team, you will leverage your expertise in computational chemistry and data analysis to support drug discovery efforts and advance their pipeline of therapeutic candidates.
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Principal Scientist, Peptide Protein Chemistry. Proficient in all aspects of modern peptide synthesis, protein bioconjugation, peptide and protein purification and analysis. Seeking a highly motivated and talented peptide chemistry leader to join our new discovery peptide research group.
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Significant expertise in protein biochemistry, including recombinant protein expression, purification and characterization is a plus. Scientists in the institute’s five academic research departments work hand-in-hand with researchers of the Scripps Research Translational Institute and Calibr to merge foundational studies in biology, chemistry and computer science with translational science to produce pioneering drugs and advances in digital and precision medicine.
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Fast-paced and collaborative environment as an Associate Scientist within the Analytical and Formulation group of Avidity’s Chemistry, Manufacturing and Controls (CMC) department. Experience in oligonucleotide chemistry and characterization methods.
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The Fleet Solutions group provides turnkey overhaul / repair, testing, and parts sales for air compressors, main propulsion steam turbines, valves, steam turbine generators, auxiliary turbines, dehydrators, pumps, strainers, PLCs, blowers, and water purification.
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Basic tissue culture and purification responsibilities include performing cell culture work, antibody purification, conjugation, and associated quality control steps including purity analysis, isotype testing, mycoplasma detection, and specificity measurement by assigned methods.
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Experienced in bioconjugation chemistry and downstream purification processes, with hands-on experience in the generation and characterization of bioconjugates. Design and execute laboratory experiments to optimize and characterize conjugation chemistries and downstream purification processes for peptide-based bioconjugates.
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The successful candidate will perform a variety of techniques, including cloning and expression of recombinant proteins, tissue culture, protein purification, and preparation for mass spectrometry analysis.
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Bachelor's degree in a relevant scientific field (e.g., Biology, Biomedical Science, Chemistry, Histotechnology), or an equivalent combination of education and experience. Histotechnician (HT)/Histotechnologist (HTL) certification from American Society for Clinical Pathology (ASCP.
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Candidates must have an MD or equivalent, DO, MD/PhD, PhD, PharmD, DrPH or other doctoral degrees in health related, bioengineering, biological sciences, cancer, cardiovascular sciences, chemistry and biochemistry, immunology, infectious diseases, marine biology, marine sciences, neurosciences, pharmaceutical sciences or social science/cognitive sciences.
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Bachelors degree or Masters degree in (Bio)chemistry, Chemical Engineering, Microbiology, Biology or related field. Must have direct experience with oligo synthesis equipment (e.g., AKTA Oligopilot, AKTA Pilot/Beckman Purification systems, Dionex/Vanquish HPLC analytical systems, rotary evaporators.
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This is an incredible opportunity for someone who is passionate about working cross-functionally in enzymology, biochemistry, and chemistry within NGS. We are looking for candidates with a solid background in molecular biology, biochemistry, photochemistry, or other related studies.
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purification chemistry jobs Company: Genomatica in Coronado, CA
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