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PhD or MS in chemistry, biochemistry, molecular biology, or chemical engineering with 10+ years of analytical development experience working in the Pharmaceutical or Biotechnology industry. In-depth technical understanding of early and late-stage development of biologics products, including CMC Regulatory, Process/Analytical Development, and GMP Manufacturing and QC release and stability testing.
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Your responsibilities will include phenotypic assay development, establishing pre-clinical in vitro/in vivo studies, performing mechanistic studies on lead drug molecules, spearheading forays into new oncology indications, and grant writing.
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Education requirementBachelor's or Master's degree in Biochemistry, Genetics, Molecular Biology or Pharmacology. Laboratory operations related to enzyme activity and inhibition. Proper maintenance of laboratory notebooks and forms in accordance with company policies and practices.
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Performs general clerical tasks, such as answering phones; updating patient appointments; retrieving, entering, revising patient electronic health records (EHR); or updating the laboratory information system (LIS) and radiology information systems (RIS.
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Bachelors Degree in Biochemistry Bioengineering Biology Cell Biology Immunology Molecular Biology or a related subject area and 4 years of scientific laboratory experience. In vitro work includes a range of cellular assays cell culture including multiparametric flow cytometry and molecular biology techniques to help interpret in vivo observations.
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The QCRG is a highly dynamic and collaborative institute, applying disease agnostic technology such as proteomics and functional genomics, as well as biochemistry, computational biology, bioinformatics, virology and drug development to unravel the molecular networks underpinning host-pathogen interactions and developing targeted therapeutics.
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Experience or knowledge with routine molecular biology techniques (DNA/RNA/protein isolation, cDNA synthesis, RT-PCR, qPCR, digital PCR, western blot, and immunofluorescence) Analyze and determine the applicability of laboratory data to draw conclusions and to make appropriate recommendations.
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Strong background in molecular biology, genetics, and synthetic biology. Our founders are experienced entrepreneurs with a history of successful startups, including the creation of Caspr Biotech, leading a confidential molecular biology organization at Amazon, and founding other successful startups.
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We are a highly collaborative team of scientists, engineers, physicians, marketers and salespeople interested in improving human health by using the latest research from diverse fields, such as microbiology, molecular biology, high-throughput genomics, distributed computing, pharmaceutical development and nutrition.
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Help to develop and optimize assays for protein, DNA, adeno associated viral (AAV) nanoparticles and related cell-based assay. The contractor Research Associate will work closely with the Analytical Development team in the Tech Dev department to help methods development and test samples utilizing PCR, ELISA, Gel Electrophoresis, cell-based and other assays; as well as to contribute to design and performing experiments with supervision as needed; complete assigned tasks within time frames with high quality; maintain a well-documented record of activities in ELN and reports.
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Other responsibilities may include utilizing nonclinical PK and PK/PD data (including use of modeling and simulation techniques) to project optimal clinical dosing regimens, doses based on pharmacological/clinical targets, human starting doses, and biomarker exploratory data (including biochemical and molecular data from quantification of mRNA, multi-panel flow cytometry, and protein expression.
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Manage analytical method transfers to CMOs/CROs for clinical phase GMP testing, and support process technology transfer to cGMP CMOs. Hands on experience in analytical method development for biologics including HPLC, CE and mass spectrometry-based methods.
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Responsibilities include, but are not limited to: Actively contribute to successful and efficient execution of robust, state-of-the-art multicolor flow cytometry methods for the characterization of CAR T manufacturing processes and products Provide analytical support for clinical-scale non-GMP IND-enabling manufacturing operations, including qualification of in-process and release methods and assist in tech transfer in support of GMP manufacturing and release of clinical material.
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3-5 years of experience in laboratory applications, including modern molecular biology techniques and NGS. The NGS (Next Generation Sequencing) Sales Specialist role involves driving sales growth, fostering strategic partnerships, and delivering customer support to clients in genomic research, clinical diagnostics, and biotechnology.
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In this vital role you will be responsible for the development and implementation of the Quantitative Clinical Pharmacology, Modeling and Simulation strategies for cutting-edge novel modalities including Bi-specific T-cell engagers, Bi-specific antibodies, oncolytic viruses, antibody-drug-conjugates, CAR-T cells-based therapies in addition to small molecule & mono-clonal antibodies.
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clinical laboratory molecular jobs in Brisbane, CA
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