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They will play an instrumental role in post-launch Life Cycle Management (LCM) and will be an integral member of the Pivotal/Commercial Biologics Technical Development Leadership Team. This team oversees late-stage process development activities, including Cell Culture, Purification, Formulation & Process Development, Analytical Development, MSAT, and Materials Sciences.
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Proficient in cloning techniques (standard, Gibson, Golden Gate) and a wide range of molecular biology protocols (including DNA/RNA purification, various PCR methods, and NGS library prep). Proficient in cloning techniques (standard, Gibson, Golden Gate) and a wide range of molecular biology protocols (including DNA/RNA purification, various PCR methods, and NGS library prep.
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Working knowledge on protein purification and hands-on experience on chromatography workstations preferred. Conduct a wide range of biochemistry, molecular and cellular biology techniques to express, purify and characterize drug candidates (e.g. DNA/RNA isolation, plasmid construction, PCR, Octet, HPLC, mammalian cell culture, transient and stable transfections.
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Leveraging a nearly 75-year legacy of innovation, our ultra-high-purity products help enable high-quality processing and production for a wide range of applications in the semiconductor, photovoltaic, lighting, aerospace, water purification, pharmaceutical, consumer electronics and telecommunications industries.
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Background in molecular biology techniques such as cloning, site-directed mutagenesis, DNA and RNA isolation and purification, sequencing, RT-PCR, and qPCR. Background in molecular biology techniques such as cloning, site-directed mutagenesis, DNA and RNA isolation and purification, sequencing, RT-PCR, and qPCR.
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Protein Purification operations contains major equipment such as chromatography columns, chromatography / TFF skids, and intermediate product vessels. BioServices encompasses Media Prep, Buffer Prep, and general equipment cleaning and preparation supporting both Cell Culture and Purification.
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Must have a thorough understanding of biochemistry and molecular biology, and experience with protein purification and troubleshooting purification protocols. Must have a thorough understanding of biochemistry and molecular biology, and experience with protein purification and troubleshooting purification protocols.
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A Ph. D in Plant Molecular Biology (molecular cloning, vector construction, genetic transformation, protein expression and purification, etc.) The ASR includes crime statistics and institutional policies concerning campus security, such as those concerning alcohol and drug use, crime prevention, the reporting of crimes, sexual assault, and other matters.
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Operates and maintains water treatment and chemical feed equipment including but not limited to, filtration, chlorination, sodium chlorite, purification, water softening, fluoridation, sludge dewatering and carbonation equipment.
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Comprehensive theoretical and practical expertise in key RNA technologies encompassing design, synthesis, purification, and quantification of RNA.Profound understanding of various biochemical and biophysical techniques, including structural biology, nucleotide chemistry, physicochemical properties of RNA, and analytical methods.
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Demonstrated experience in process development for fermentation product purification. This will require configuring the initial process flowsheet from a blank sheet of paper for purification of new fermentation products.
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Strong practical knowledge of downstream purification of mammalian and insect cell culture processes. · Prior viral vector purification experience is desired. · Experience in scale up and scale down of purification processes.
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Monitors and maintains water purification equipment: including charcoal filter, water softener, reverse osmosis, and demineralizer anion/cation system for purifying water. Monitors and maintains water purification equipment: including charcoal filter, water softener, reverse osmosis, and demineralizer anion/cation system for purifying water.
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B.A./B.S degree in Chemical Engineering, Biology, or similar relevant field with at least 6 years of direct GMP manufacturing experience in a biotechnology manufacturing facility or Pilot Plant OR a High School Diploma with 10 years of experience in protein purification in Biotech/Pharmaceutical industry.
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The Manufacturing Associate I/II participates in the manufacturing of biopharmaceutical drug product to support MacroGenics' multiple clinical programs in the Protein Purification area. Knowledge of protein purification techniques.
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purification job
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