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Strong understanding state-of-the-art methods and technologies used in the industry Tissue handling techniques for detection of gene and protein expression, including fixation, sectioning, IHC, histological staining, ISH MAbs/bi specifics - expertise in antibody protein structure & function, ability to apply protein engineering principles to mAb drug design.
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The ideal candidate will have expertise in protein engineering techniques, including phage, yeast, or mammalian cell display, experience optimizing expression and purification of antibody fragments (e.g. minibody and Fc-fusions) and have a working knowledge of antibody structure and function.
$122,000 - $168,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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This person will closely interact with the principal investigator and work on research focused investigating the mechanistic roles of protein machinery involved in protein degradation (e.g. proteasome) using various in vitro and in vivo methods (e.g. mechanistic enzymology, cell culture & C. elegans.
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Competence in nutritional content, sources and use of commercial supplements, tube feedings, human milk, infant formulas and feeding modulars (fat, protein, carbohydrate, vitamins and minerals.
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Knowledge of protein biochemistry and associated characterization techniques (UV-Visible spectroscopy, HPLC-SEC/IEX/bio-affinity methods, rheology) is required; Hands-on experience with tangential flow filtration (TFF) of protein solutions is desirable.
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Viral DNA, RNA and protein extraction, purification, and analysis, including cloning, amplification and DNA sequencing. Viral DNA, RNA and protein extraction, purification, and analysis, including cloning, amplification and DNA sequencing.
$50,620 a yearExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Skills: HPLC, SOP, In Vitro, In Vivo, Protein Purification, GMP (Good Manufacturing Practice) The purification group is responsible for non-GMP protein- drug lead generation, supporting the various company research units and their pre-clinical therapeutic in- vitro and in- vivo needs.
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Ph. D. degree in biology, computational biology, bioinformatics or other related discipline with 2+ years relevant experience in data science and protein modeling and antibody analysis or M.S. in biology, computational biology, bioinformatics or other related discipline with 6+ years of industry experience in data science and protein modeling and antibody analysis.
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Research: assist in cloning; bacterial, yeast, and mammalian cell culture; protein purification; mouse husbandry and surgery. Research duties will entail assisting in cloning; bacterial, yeast, and mammalian cell culture; protein purification; mouse husbandry and surgery.
$36,368 - $50,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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These techniques play a key role in fields such as metabolic imaging, protein dynamics studies, drug discovery and metabolomics, organic and inorganic materials studies and many other areas. Our team is devoted to identifying, developing, producing and marketing innovative products in the fields of Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS) and Magnetic Resonance Imaging (MRI.
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Laboratory experience in protein purification including at least some of the following chromatography methods: protein A affinity, ion exchange, hydrophobic interaction, immobilized metal affinity and size exclusion.
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Develop methods to quantitatively measure the purity and heterogeneity of AAV gene therapy vectors, including empty capsid, aggregation, and capsid protein purity. Knowledge of analytic methods for quantification and characterization of AAV vectors and Protein.
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CONSIDERED EXPERIENCE INCLUDES: Research Associate Scientist Analytical Chemist Bioanalytical Support Peptide Synthesis Protein Conjugation Custom Antibody Development Gene to Protein Expression DiedreMoire #JobSearch #JobHunt #JobOpening #Hiring #Job #Jobs #Careers #Employment #jobposting #BioTechJobs #BioTechnologyJobs #AnalyticalChemist #PharmaceuticalJobs #ScientistJobs.
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Proficient in protein-based assay development including ELISA, enzymatic activity assay, AlphaLisa, etc. Strong expertise in protein-peptide, protein-small molecule or protein-protein interaction characterization, including SPR, BLI, FP (fluorescence polarization), Mass spec, DSF, ITC, etc.
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Experience in performing protein assays such as ELISA and enzyme activity is a plus. The Senior Research Associate will be a key player in driving genomic medicine pipeline project through target validation, candidate selection and IND-enabling phases using in vitro, in vivo and ex vivo studies.
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