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Proven expertise in membrane protein purification by affinity chromatography, SEC, IEX using AKTA systems. The successful candidate will perform laboratory research including membrane protein purification, structure determination, biophysical/biochemical characterization and cell-based assays using state-of-the-art resources.
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Experience with protein purification using an AKTA system and protein characterization using HPLC (analytical SEC), SDS-PAGE, and mass spectrometry. The successful candidate will have a strong background in bacterial expression and protein biochemistry, ideally hands-on experience with small molecule drug discovery.
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Apply knowledge in protein biochemistry, biophysics and mammalian cell biology to support drug discovery at ViiV. The selected candidate will be a highly motivated self-starter and will have the opportunity to work alongside antibody engineers, protein scientists, virologists, and chemists in a dynamic and multidisciplinary team environment.
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REQUIREMENTS:Successful candidates will have a recent Ph. D. in virology, immunology, biophysics, structural biology, or other related fields. Dr. Zhu's laboratory takes an interdisciplinary translational approach to vaccine development, integrating structure-based antigen design, protein nanoparticle engineering, animal testing, and mechanistic analyses including viral neutralization assays, immunohistochemistry, and B cell analysis.
$64,480 - $70,000 a yearFull-timeExpandApply NowActive JobUpdated 4 days ago - UpvoteDownvoteShare Job
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Analysis of proteins and protein complexes using Transmission Electron Microscopy (TEM) and Cryogenic Electron Microscopy (Cryo-EM). PhD in Structural Biology, Biophysics, or similar discipline.
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A strong understanding of protein biophysics and structure. We are seeking a creative, motivated Computational Scientist with a strong background in Protein Design. PhD in Computational Biology, Computer Science or a related field with demonstrated experience working on protein-related applications.
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Description :Required QualificationsEducation: PhD in biochemistry, biophysics, structural biology, computational biology, or related field. Job Duties OutlinedResearch Overview: Work with PI/faculty mentor and other laboratory members, to analyze and interpret large scale quantitative proteomics datasets generated using cross linking mass spectrometry studies on affinity purified protein complexes, isolated organelles from cells and tissues, and complete networks from cells and tissues.
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Key Functional Requirements & Qualifications: Advanced degree (PhD) in a field related to AI/ML or Data Analytics such as: Computer Science, Mathematics, Statistics, Physics, Biophysics, Computational Biology or Engineering Sciences.
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The candidate should have a strong background and training in theory and computational science related to molecular biophysics and biomolecular modeling, and ideally should have significant prior research experience and publications in simulations of protein/ligand interactions as well as in usage of MD simulation software (e.g., NAMD, AMBER, GROMACS, etc.
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Expert in enzymology, enzyme kinetics and current assay formats for multiple enzyme classes and protein-protein-interaction targets. The Director of Small Molecule Biochemistry and Biophysics will be responsible for assisting in the development and expansion of the small molecule research unit at Novo Nordisk.
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Support general lab activities such as: making solutions and buffers as needed and performing basic molecular cloning (primer design, PCR, DNA/RNA purification), as well as performing protein expression and protein purification and other molecular biology techniques.
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Perform low and high-throughput screens using the Biacore 8K SPR for hit discovery, medicinal chemistry SAR support, and detailed evaluations of protein-antibody and protein-peptide interactions.
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Strong record of conducting high-quality research either in structural biology or molecular biology with prior experience in protein biochemistry. Ph. D. in biochemistry, biophysics, chemistry, microbiology, or a related field.
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Requisition Id 12888 Overview The Diffraction Group in the Neutron Scattering Division (NSD) at Oak Ridge National Laboratory (ORNL) has an immediate opening for a postdoctoral Protein Chemist or Structural Biologist to join a multi-disciplinary research team in development and application of paramagnetic labeling and proton polarization techniques for structure analysis.
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We have the capabilities to analyze virtually any peptide, protein, or antibody, and have built a reputation for solving technical challenges related to assay development and validation. B.S. or M.S. in molecular biology, biochemistry, biophysics, immunology, or a related field with at least 1 year of experience.
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