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We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development.
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Design toxicity studies: coordinate with Preclinical Outsourcing for placement and monitoring of the studies as well as the Bioanalytical and DMPK groups regarding integration of bioanalysis and toxicokinetic aspects into these studies to ensure on-time delivery of key data and study reports.
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You will work with experienced pharmacometricians, Preclinical Pharmacokinetics, Drug Metabolism, Toxicology, and Clinical Pharmacology colleagues to provide inputs to overall product development plans and to address research and development objectives and issues.
$1 - $2ExpandApply NowActive JobUpdated 25 days ago - UpvoteDownvoteShare Job
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Independently develop and execute analytical methods to propel in vivo pharmacology and functional assays from our rodent and NHP studies i.e., ddPCR/qPCR-based RNA/DNA quantification; and ELISA/Western blot-based protein assays.
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Establish effective communication with cross-functional colleagues including those from medical, clinical pharmacology, preclinical biology and biometrics. The successful candidate will work closely with our Preclinical Research Team and our Clinical Development Team to develop clinical biomarker strategies for development candidates.
Full-timeExpandApply NowActive JobUpdated 9 days ago - UpvoteDownvoteShare Job
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MS in Pharmacokinetics, Pharmaceutical Sciences, Pharmacology, Chemistry, Biochemistry, or related field with a specific focus on PK and PK/PD modeling and simulation and 10+ years of Pharmaceutical/Biotech industry experience in conduct and/or oversight of late-stage Modeling and Simulation activities, including conduct or oversight of small molecule population pharmacokinetic analyses.
$91ExpandApply NowActive JobUpdated 10 days ago - UpvoteDownvoteShare Job
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Anesthesiologists, other physician scientists, and PhD-scientists with strong records of translational research related to anesthesiology including disciplines such as pain medicine, neuroscience, echocardiography, clinical pharmacology, perioperative analytics, bioengineering, and personalized medicine are encouraged to apply.
ExpandApply NowActive JobUpdated 21 days ago - UpvoteDownvoteShare Job
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Planning and execution of mechanistic PKPD analyses to integrate knowledge of drug design parameters, disease pharmacology, physiology, pharmacokinetics and pharmacodynamics, and to optimize selection doses and preclinical study designs.
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Doctorate (PhD), PharmD, DVM, or MD degree or equivalent in Toxicology, Pharmacology, or a related discipline strongly preferred. Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance.
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It has established strategic collaborations with GSK, Amgen, Pfizer and Gilead supporting certain clinical and preclinical pipeline programs. Strong knowledge of model-informed drug development, DMPK-Clinical Pharmacology concepts, and regulatory requirements to support clinical development and regulatory submission.
$223,449 - $337,470 a yearFull-timeExpandApply NowActive JobUpdated 16 days ago - UpvoteDownvoteShare Job
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Based on the successful progress of our R&D platform, including expertise in medicinal chemistry, immune cell biology and in vivo pharmacology, Nurix is advancing multiple programs to the clinical stage.
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The Toxicologist will collaborate with external vendors, the internal preclinical pharmacology and toxicology team, and other stakeholders across the company to ensure efficient processes that scale with Verve’s continued growth.
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An exciting opportunity is available for a Director to join the In Vivo Pharmacology & Biomarker Discovery team of the Institute of Medicine (IOM) at Altos Labs. We are seeking a highly experienced and talented Director of In Vivo Sciences to conceptualize and lead our in vivo preclinical research supporting portfolio progression.
ExpandApply NowActive JobUpdated 21 days ago - UpvoteDownvoteShare Job
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Work collaboratively with partners in molecular and cellular biology, pharmacology, computational chemistry, ADME, structural biology, chemical development, and other key functions. Our mission requires critical thinking, a portfolio approach and deep scientific expertise in several fields including oligonucleotide chemistry, bioconjugation chemistry, nanotechnology, cellular and molecular pharmacology and screening technologies coupled with an ability to work collaboratively with internal and external partners.
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Or from an accredited college or university according to the Council for Higher Education Accreditation (CHEA. Foreign degrees must be evaluated for equivalency Demonstrated expertise in applying experimental methods that are relevant for investigating drug MOA and pharmacology, for example methodology from the fields of cell biology, immunology, genetics, genomics, molecular biology, biochemistry, chemistry, enzymology, pharmacology, drug discovery and/or similar disciplines.
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