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Experience with ELISA and MSD for running high-throughput multiplexed immunoassays. Nice-to-haves include prior experience with automation, antibody engineering, BLI, and mammalian cell culture.
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Expertise in Ligand Binding Assay Methods (ELISA, MSD, Gyrolabs, Simoa etc.) Moderna’s Bioanalytics group is seeking an Associate Director with strong hands-on experience in ligand-binding assays, including pharmacokinetics (PK), pharmacodynamics (PD), and anti-drug antibody (ADA) assessments, to quantify mRNAs, proteins, and antibodies against therapeutic proteins.
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Experience using multi-color flow cytometry to immunophenotype human cells from blood and tissues preferred as is hands-on experience using MSD, Luminex or ELISA to measure analytes in serum, plasma, supernatant or cell lysates is required.
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Various assays across multiple product types, including mAb, oligonucleotide, and DS/DP AOC (Antibody oligonucleotide conjugate). Avidity Biosciences, Inc.'s mission is to profoundly improve people's lives by delivering a new class of RNA therapeutics - Antibody Oligonucleotide Conjugates (AOCs.
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Experienced in immunoassay platforms that include three of the following: MSD, ELISA, Luminex, Gyros, Quanterix, Ella. Immunoassay development, validation and sample analysis of PK/PD, Anti-Drug Antibody (ADA) and soluble protein biomarkers in support of biologic drug development in a GLP environment or similar.
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Lead internal development of novel analytical methods to characterize LNP components and products, including HPLC, LC-MS, CE, DLS, ELISA, and plate-based assays. Manage internal routine and non-routine analysis of lipid, mRNA, antibody, antibody conjugates, and targeted LNP drug products.
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Execution, troubleshooting and design of antibody purification and characterization work such as gel-electrophoresis, ELISA, AlphaLISA, BLI, SPR, UV spectroscopy and data analysis. This role requires technical expertise in the areas of molecular and cell biology, biochemistry, informatics, antibody display, antibody discovery, and protein structure-function.
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Willingness to learn new immunoassays such as ELISA, ELISPOT/FluoroSpot, neutralizing antibody, MSD, cytokine release and flow cytometry. We became a wholly-owned, independently operated, subsidiary of Bayer AG in late 2020 as a cornerstone of its newly formed Cell & Gene Therapy (CGT) platform.
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Screen libraries via common affinity characterization methods such as ELISA, MSD, BLI, and FLOW cytometry. Proficiency with immunoassays; such as ELISA, MSD, and bio-layer interferometry (BLI), and flow cytometry is desired.
Full-timeExpandApply NowActive JobUpdated 3 days ago - UpvoteDownvoteShare Job
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Extensive experience with antibody bindingassays and analysis, especially ELISA, biosensor, and multi-color flowcytometry is required. Implement and routinely run disease-relevant in-vitro and in-vivo teststo probe for antibody therapeutic efficacy.
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Experience with protein expression, purification, and characterization using analytical methods such as SDS-PAGE, Western blot, HPLC, and ELISA. Experience with multispecific antibodies, fusion proteins, and other non-traditional antibody formats is a plus.
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Experience with wet lab immunological assays (ELISA, Flow cytometry, Functional/Reporter) Take an active role in ML/AI roadmap development for novel antibody designs, driving information system infrastructure readiness for binding and functional assay data, and establishment of best practices in advanced knowledge base analytics.
Full-timeExpandApply NowActive JobUpdated 9 days ago - UpvoteDownvoteShare Job
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Execute molecular and cell-based methodologies including flow cytometry, immunohistochemistry, cytotoxicity assays, reporter assays, ELISA, western blotting, WES and in vitro PD assays. Investigate novel antibody drug conjugate (ADC) targets, linker payloads and new MOAs of our therapeutics through development, optimization, and execution of complex assays.
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Experience with ELISA, antibody/antigen selection and conjugation, protein purification, SDS-PAGE, Western blot, etc. Experience with ELISA, antibody/antigen selection and conjugation, protein purification, SDS-PAGE, Western blot, etc.
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In-depth experience with developing ligand binding assays (e.g., ELISA, MSD, AlphaLISA, Simple Plex, Luminex). The Scientist will have hands-on experience in ligand binding/antibody assay development and will be interested in projects requiring close collaboration with other groups, such as discovery research, product sciences, process development, and QC.
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