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Hands on experience with ADC chemistry, reaction processes and purification methods (i.e., Tangential flow filtration, chromatography, etc. Technical knowledge at design, execution and data interpretation of experiments related to development, optimization, and scale-up of biologics with a focus on ADC BioConjugation and Purification processes.
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Success in this position requires the use of a variety of skills to identify, analyze and implement opportunities for improvement within our laboratories for cell culture, protein/antibody purification, immunoassay reagent preparation, as well as the complete production cycle from production to shipment.
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Manufacturing cGMP production activities include solution preparation, master/working cell bank production, upstream cell culture, downstream protein purification, mRNA and molecular therapeutics production, and small-scale fill/finish.
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A broad range of functional expertise in modern synthetic organic chemistry, compound purification, spectral analysis and interpretation. Responsible for developing and executing organic chemical processes that provides practical access to potential therapies, which may include small molecules and/or antibody drug conjugates.
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Develop recovery and purification process that utilizes clarification, chromatography, and membrane filtration technologies for monoclonal antibodies, bio-specifics and antibody drug conjugates (ADC.
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Main Duties & Responsibilities This position is a laboratory-based role, the main responsibility will be the development of conjugation and purification processes for antibody-drug conjugates (ADCs.
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The Head of PMV oversees an organization of over 100team members including scientists, engineers and associates responsible for QC microbiology supporting all South San Francisco GMP production operations, adventitious agent testing, process virology R&D and validation, purification processes development and transfer to manufacturing operations from non-clinical studies to the registration stage of biologics.
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Antibody purification, protein conjugation and labeling. immunology, Laboratory, biochemistry, glp, gmp, biology, elisa, antibodies, aseptic technique, iso 13485, Chemistry, assay development, assay.
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Experience with diverse purification approaches for different antibody formats, analytical characterization (SEC-HPLC, cGE, mass spec, cIEF, SEC-MALS), and developability assessment (thermal stability, poly specificity, hydrophobicity, forced degradation, serum stability) is required.
$158,500 - $192,900 a yearFull-timeExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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Expert in ELISA techniques, flow cytometry, cell culture, immunoassays, antibody purification, and mouse handling, including immunizations, spleen removals, hybridomas, etc. These include intellectual input and decision-making on protein targets to be pursued, development of immunogens and immunization strategies, utilization of hybridoma technology, and antibody validation in vitro and in vivo.
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Experience in radiolabeling, purification, validation, and development of antibody-based nuclear imaging probes in clinical/pre-clinical settings is preferred. Prepares non-radioactive compounds for radiochemistry (e.g., antibody fragmentation, electrophoresis, cell culture, etc.
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We are looking for a highly motivated, independent, and skilled Research Associate to join the Quality Operations team at Kodiak Sciences to work on antibody purification, characterization, formulation, and conjugation.
$125 - $150ExpandApply NowActive JobUpdated 4 days ago - UpvoteDownvoteShare Job
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Including target selection, hit generation and optimization, protein expression/purification, and antibody engineering. Abpro is seeking an exceptional individual to lead our antibody discovery efforts and develop a rich pipeline that leverages the unique advantages of our technology platforms.
$150 - $200Full-timeExpandApply NowActive JobUpdated 4 days ago - UpvoteDownvoteShare Job
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You have experience working with and developing assays (keywords include: lateral flow assays (LFA), immunoassays, ELISA, In Vitro Diagnostics (IVD), point-of-care diagnostics, rapid diagnostic tests, paper-based sensors, biosensors, microfluidic, bioconjugation, nanoparticle conjugation, antibody purification.
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Hands on experience with AKTA instrumentation or protein purification. Familiarity with purification processes, AKTA or FPLC instrumentation, HPLC/UPLC instrumentation or using Unicorn, Empower, or PMI software.
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antibody purification jobs
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