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Cloning recombinant protein and antibody constructs (including reformatting to scFv, bispecifics) using a variety of molecular biology techniques including Polymerase Chain Reaction, Gibson assembly, DNA purification, and transformation.
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Research Associate, Protein Science, protein expression, purification, microbial cell culturing, molecular cloning, biochemical synthesis, FPLC, SDS-PAGE, ELISA, colorimetric assays, Microsoft Office.
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Must have experience with DNA/RNA handling and purification. Existing collaborations within CZ Biohub: Technology Platforms (Bioengineering, Computational Microscopy, Data Science, Genomic Sequencing, Mass Spectrometry/Proteomics), and Research Group Leaders.
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Experience developing and working with various antibody discovery and protein engineering technologies such as mouse hybridoma, single B cell, phage/yeast/mammalian display, and/or computer-aided antibody/protein design is required.
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Tissue cultureMolecular cloning and DNA assembly with E. coliPCRDNA electrophoresisDNA purification and cleanup (i.e. PCR cleanups, gel purification)Restriction digestion, ligation (or other assembly techniques)DNA transformationPlating microbial transformation on appropriate conditionsPlasmid DNA purification (i.e. mini prepping)DNA sequence sample preparation (sanger) and analysisExcellent sterile techniqueExcellent pipette and liquid-handling techniqueExcellent record-keeping.
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Produce NGS amplicon libraries for antibody repertoire analysis. Clone and express recombinant antibodies in 293 cells and confirm antibody binding by ELISA. OmniAb provides our pharmaceutical industry partners access to the most diverse antibody repertoires and cutting-edge screening technologies to enable discovery of next-generation therapeutics.
$114,000 - $127,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Hands on experience with ADC chemistry, reaction processes and purification methods (i.e., Tangential flow filtration, chromatography, etc. Technical knowledge at design, execution and data interpretation of experiments related to development, optimization, and scale-up of biologics with a focus on ADC BioConjugation and Purification processes.
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Throughput cell analysis, phenotyping, protein chemistry and antibody cell analysis. throughput cell analysis, phenotyping, protein chemistry and antibody cell analysis. named Ghost Cytometry (GC) which combines high-speed imaging and machine learning to analyze and.
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We develop, manufacture and sell instruments, biosensors, reagents, and consumables for antibody, gene and cell therapy development. Coordinate sales efforts with Field Application Scientist (FAS) and the Service team for successful product demonstrations, sample workups, and post-sales support.
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Are excellent in most of the following: bacterial culturing, PCR, gel electrophoresis, molecular cloning, plate reader assays, cell-free expression systems, protein purification, buffer and media preparation, and DNA purification, sequencing, and analysis.
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Coordinates with Cancer Immunology, Protein Chemistry, Antibody Engineering, and Translational Oncology groups to advance lead molecules of the projects. Familiarity with automated or semi-automated instrumentation, while not required, would be advantageous, as would familiarity with the multi-disciplinary activities of antibody lead profiling.
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Is looking for a talented postdoctoral researcher interested in developing and implementing high-throughput techniques to study viral protein and antibody evolution. Defining the biophysical constraints on antibody affinity maturation.
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Perform research on projects working with nucleic acid purification, qPCR, molecular cloning, next-generation sequencing, Western Blot, ELISA, fluorescence microscopy, and flow cytometry. Perform research on projects working with nucleic acid purification, qPCR, molecular cloning, next-generation sequencing, Western Blot, ELISA, fluorescence microscopy, and flow cytometry.
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Knowledge in oligonucleotide manufacturing (including synthesis, liquid handling, purification and quality control) is highly preferred. GENEWIZ is a leading global genomics service company and trusted provider for DNA sequencing, gene synthesis, molecular biology, next generation sequencing, bioinformatics, and GLP regulatory services.
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Responsibilities Design, optimize, and scale-up downstream processes for the purification of viral vectors, with a focus on AAV and lentiviral vectors. Collaborate with cross-functional teams, including Upstream Process Development, Analytical Development, and Manufacturing, to ensure seamless integration of processes.
$115,000 - $150,000 a yearFull-timeExpandApply NowActive JobUpdated Yesterday
antibody purification jobs in Alameda, CA
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