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With a combination-focused pipeline that exploits the power of six scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy and Epigenetics) to help address unmet clinical needs in a host of hematological cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death.
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This position reports to the head of clinical pharmacology and toxicology and liaises with clinical development, clinical operations, non-clinical pharmacology and toxicology, and drug discovery to execute activities for advancing the development pipeline.
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We are seeking a highly motivated Senior Scientist who will contribute to the discovery of novel oncology medicines that include T Cell Engagers and Antibody Drug Conjugates for haem and solid tumor indications.
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Pharma: Counter ions, Leachables and Extractables, and Ionic Impurities in Drug Discovery, Development, Manufacturing. BioPharma: Monoclonal Antibody Characterization. Electronics, Power: Ionic impurities in High Purity Water and ReagentsSUMMARYReporting directly to the Director of Operations, Sunnyvale, CA, this position directs and coordinates activities of personnel engaged in Manufacturing Planning, Purchasing, Warehouse Operations, Inventory Control, Customs Compliance, Order Management of plant manufacturing operations.
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Hands-on experience with in vitro antibody discovery display technologies (e.g., phage, yeast display) Discovery Biotherapeutics and Genetic Medicine at AbbVie is seeking a highly motivated research scientist to join a dynamic team supporting biologics drug discovery and engineering.
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At Genentech Computational Sciences (gCS) Prescient Design, we are revolutionizing drug discovery with cutting-edge machine learning techniques. Participate in cutting-edge research in machine learning and methods development for scientific discovery, including large language models and drug discovery.
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Perform integrative analysis of multiple biomarker assessments including gene expression, IHC/Multiplex IF data, safety biomarker, and drug response data for baseline and post-dose biomarker discovery for clinical programs.
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Apply knowledge in protein biochemistry, biophysics and mammalian cell biology to support drug discovery at ViiV. Engage and network with scientific leaders in drug discovery across ViiV R&D.
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As core member of multi-disciplinary drug discovery teams, you will direct investigative toxicology strategies to predict, assess and mitigate target- and modality-related safety risks in discovery programs, with a focus on Antibody-Drug Conjugates.
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BUSINESS AREABiologics Engineering (BE) is large global organization with teams in Cambridge, UK and Gaithersburg MD responsible for the discovery and optimization of next generation biologics to create biological drug candidates for all key therapeutic areas such as oncology, respiratory and inflammation, cardiovascular, renal and metabolic diseases.
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In collaboration with AbbVie About the Role: Plays a key leadership role in developing our in vitro and in vivo strategies towards target identification and drug discovery, through to clinical candidate selection.
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Strong understanding of drug discovery and development processes, including preclinical, clinical, and regulatory requirements. CytomX has a broad pipeline, which comprises seven therapeutic candidates across multiple treatment modalities including antibody-drug conjugates ("ADCs"), T-cell engaging bispecific antibodies ("TCBs"), and immune modulators such as cytokines and checkpoint inhibitors ("CPIs.
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Industry or Academic experience in drug development required with experience in malignant haematology clinical trials strongly preferred. Drug Development/Clinical Development Planning: Demonstrates a consistent track record to both independently complete, and lead peers in completion in components of sophisticated plans, related documents, appropriate methodologies, measures, analytical plans and evaluation tools.
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Reporting to the Oncology Discovery Therapeutic Area head, you will partner with data science and machine learning (DSML), translational oncology and computational biology colleagues to gain deep insights into the biology and efficacy of antibody drug conjugates (ADCs) with the goal of delivering therapeutics to the right patients.
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This is your chance to join our Tumor Targeted Delivery team in Early Oncology in Gaithersburg, MD USA. As a Senior Scientist, you will lead target validation efforts for tumor-targeted therapies, such as antibody-drug-conjugates (ADCs) and targeted radio-conjugates.
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