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The Program Leader in Metabolic Diseases Research will direct all drug discovery research activities from lead generation to IND and contribute to early clinical studies related to the programs.
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The Small Molecule Discovery Center (SMDC) at UCSF is seeking a highly collaborative biologist or biochemist with a passion for drug discovery and chemical biology. When biomedical research at UCSF uncovers new potential targets for drug discovery, the SMDC works with researchers to develop chemical tools and drug leads to further understand and exploit these targets for human health.
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As part of the Discovery Biotherapeutics efforts at BMS, the Principal Scientist will play a key role in advancing antibody drug conjugates technologies at BMS. The Discovery Biotherapeutics team at BMS seeks to understand the structure and function of complex molecules such as bispecific antibodies, antibody drug conjugates and endogenous proteins in order to optimize their utility as therapeutic agents.
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The candidate is expected to have strong collaborative skills to ensure robust partnerships with biologists, antibody discovery and engineering & bioanalytical scientists to advance ADC projects.
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You will lead internal peptide therapeutics development projects from drug discovery to Phase-2 clinical trials. Qualifications: Leading expert in peptide drug discovery and development with a strong record of prior discoveries and/or peer-reviewed publications.
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Closely interact with scientists in biology, chemistry, and other functional teams to provide in vitro assay and screening expertise for drug discovery. The ideal candidate is an expert assay biologist who thrives on rigorous experiment design and execution, contributes to various drug discovery projects and is a consummate team player.
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This position offers a unique opportunity to work in a dynamic and innovative environment developing your career at the interface of mechanistic research, drug discovery, and preclinical drug development.
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The position involves collaboration with protein science, in-vivo biology, single-cell sequencing, bioinformatics, translational and clinical teams to execute and advance HiFiBiO's drug discovery and translational research.
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Strong subject matter expertise in immune-oncology, cell therapy drug discovery and development including CMC considerations, CAR design, engineering and armoring strategies, innate immune cells such as NK and gamma delta for the purposes of leading drug development projects from start to the clinic.
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Chemistry is a core capability in Small Molecule & Drug Discovery with innovative scientists working in medicinal chemistry, radiochemistry, analytical chemistry, and large-scale synthesis.
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The ideal candidate should have an outstanding scientific reputation in the field of machine learning research for computational biology and a demonstrated passion for solving biological problems relevant to drug discovery.
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As a Scientist, you will have a unique opportunity to contribute to the success of the Bioscience Immunology drug discovery pipeline. This drug discovery research position will support and collaborate with a research team to identify and validate disease-modifying molecular targets and support the progression of drug development projects to clinic.
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PhD. in computational biology, bioinformatics, or other biomedical sciences with a minimum of seven years' experience in applying bioinformatics approaches to drug discovery/development, preferably in a biopharma setting.
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HemaCare, a Charles River company, is a global leader and trusted brand in the customization of human-derived biological products and services for biomedical research, drug discovery, and cell and gene therapy development.
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The successful candidate also will have the opportunity to help investigate new technologies related to drug delivery, pharmaceutics, and other areas relevant to Merck’s drug discovery/development programs.
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