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Scientist / Senior Scientist, Biochemistry
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Full-time
- Flare's drug discovery efforts to target switch sites has rapidly advanced, resulting in an emerging pipeline of research programs that address well-validated genetically-defined transcription factors, initially focused on precision oncology with future potential in neurology, rare genetic disorders, immunology and inflammation.
- The candidate's primary role will be to develop and execute novel assays based on the company's proprietary switch site framework to both support on-going medicinal chemistry efforts as well as to identify and characterize novel small molecules targeting transcription factors.
- Act as Biochemistry group representative, collaborating closely with Chemistry, Structural Biology, Proteomics, and Biology colleagues to define strategy towards the mechanistic understanding of small molecule modulators of transcription factors to improve compound efficacy for H2L and LO advancement
- Work with Protein Biochemistry and Structural Biology colleagues to design, generate, and characterize protein reagents needed for pre-clinical drug discovery
- You have a BS or MS with significant industry experience or a PhD w/ 2+ years industry experience in biochemistry, biophysics, or related field.
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