Takeda Pharmaceutical Company Ltd

Join Takeda as a Research Scientist II, Inflammation Discovery Research where you will be empowered to design, execute and analyze discovery immunology and in vitro preclinical pharmacology studies of inflammation and autoimmunity with a focus on TYK2 inhibition for multiple disease indications.. As part of the GI and Inflammation Drug Discovery Unit (GI DDU), you will report to the Associate Director and work with the organization.. Utilize a battery of in vitro assay technologies in primary cell types and cell lines to execute on programs including (but not limited to): ELISA, qPCR, flow cytometry, immunofluorescence microscopy.. Work with flow cytometry, in vivo pharmacology, histopathology, and bioinformatics team to evaluate cell and molecular action of TYK2 inhibition.. Demonstrate significant knowledge of basic Immunology and in vivo pharmacology.

research scientist ii

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description About the role: At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide. Join Takeda as a Research Scientist II, Inflammation Discovery Research where you will be empowered to design, execute and analyze discovery immunology and in vitro preclinical pharmacology studies of inflammation and autoimmunity with a focus on TYK2 inhibition for multiple disease indications. You will also identify and implement new assay technologies that have an impact on project advancement, assay throughput and/or assay performance. As part of the GI and Inflammation Drug Discovery Unit (GI DDU), you will report to the Associate Director and work with the organization. How you will contribute: Initiate investigation of new experimental approaches to a wide range of problems using scientific theory and technical literature with a focus on TYK2 pathway. Utilize a battery of in vitro assay technologies in primary cell types and cell lines to execute on programs including (but not limited to): ELISA, qPCR, flow cytometry, immunofluorescence microscopy. Design and execute complex cell-based assays including co-cultures, 3D microtissues / organoids. Independently plan and execute experiments for a research work group or project, troubleshoots complex problems and/or specialized procedures, and changes experimental design if necessary. Interpret and analyze data, to incorporate results into overall scientific projects; Independently generate novel hypothesis and integrates data produced by other disciplines. Develop and validate new technical and analytical methods using literature. Exercise independent judgement (selecting most appropriate methods, coordinating efforts, evaluating criteria for obtaining results). Prepare detailed protocols / SOPs that enable transfer of validated assays to project team members and collaborators. Work with flow cytometry, in vivo pharmacology, histopathology, and bioinformatics team to evaluate cell and molecular action of TYK2 inhibition. Contribute to functional scientific discussion. Maintain detailed laboratory records and contribute to drafting of study reports. 80% lab based at the San Diego facility. Minimum Requirements/Qualifications: PhD degree in a scientific discipline with 2+years relevant experience; post doc and industry experience preferred, or MS with 8+ years experience, or BS with 10+ years experience. Demonstrate significant knowledge of basic Immunology and in vivo pharmacology. Communicate and collaborate with colleagues effectively. Knowledge in the use of common analytic softwares including Microsoft Office programs, Graphpad Prizm etc. With latitude in specific areas, plans and executes experiments with appropriate controls; decisions have moderate to advanced scope and impact technical operations or project deadlines. What Takeda can offer you: 401(k) with company match and Annual Retirement Contribution Plan Tuition reimbursement Company match of charitable contributions Health & Wellness programs including onsite flu shots and health screenings Generous time off for vacation and the option to purchase additional vacation days Community Outreach Programs More about us: At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work. Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. Base Salary Range: $124,600.00 to $178,000.00, based on candidate professional experience level. Employees may also be eligible for Short-term and Long-Term Incentive benefits as well. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program and Paid Volunteer Time Off. The final salary offered for this position may take into account a number of factors including, but not limited to, location, skills, education, and experience. In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply. #LI-SGM #LI-Onsite EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations San Diego, CA Worker Type Employee Worker Sub-Type Regular Time Type Full time #J-18808-Ljbffr

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