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Support process Improvement projects such as standardization of test methods and the execution of test methods as well as assay validation/ qualification. Keywords: ELISA, Biochemistry, SDS PAGE, Gel Electrophoresis, UV-Vis, GMP, Laboratory, Investigations, Microbiology, Pharmaceutical.
$40 an hourFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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As a senior BESM, you will manage the bioanalytical support externalized to CRO partners covering method development, assay transfer/validation (including cross validation), and work closely with internal team members to define timeline, outsourcing strategy, and develop new processes for outsourcing to better optimize the outsourcing workflow.
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Engage in a team environment, demonstrating a drive for learning and innovation in assay development. Apply technical expertise in quantitative mass spectrometry assays to advance biomarker discovery and support therapeutic development.
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The individual will be responsible to lead vaccine bioanalytical assay development, qualification/validation, technology transfer, and/or troubleshooting to meet regulatory expectations for validation and line of sight for life-cycle maintenance.
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Experience in in-vitro potency assay development for Cell & Gene therapy products. This researcher should have a background in assay development, preferably in cellular and molecular immunology and immune oncology, while also possessing strong interpersonal skills and the ability to work collaboratively with other groups within the organization.
$145,000 a yearFull-timeExpandApply NowActive JobUpdated 11 days ago - UpvoteDownvoteShare Job
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Working knowledge and hands-on experience with vaccine related assay development, will be a plus. Assist in analytical testing of critical reagents to ensure long term bioanalytical assay robustness using a variety of different analytical tools.
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Experience in technical platforms that include IHC, immunoassay, PCR, NGS and novel assay technologies (digital pathology, liquid biopsy, multiplex technologies). Experience in technical platforms that include IHC, immunoassay, PCR, NGS and novel assay technologies (digital pathology, liquid biopsy, multiplex technologies.
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The individual should have a knowledge of the principles and concepts of various techniques to assist in integration and operation of various liquid handlers and laboratory equipment, facilitate assay data results, and produce visualization to assess assay results.
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Skills: DNA/ RNA/ Protein isolation, cell culture, flow cytometry, ELISA, western blot, qPCR, gene knockout, microscopy, primer design, protein purification and functional assay. The Preclinical Sciences & Translational safety (PSTS) group in collaboration with Cell Therapy group in Therapeutics Discovery (TD) seeks a motivated post-doctoral candidate to develop a novel assay to assess genomic safety of nuclease mediated gene editing.
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Under minimal direction from the manager, performs raw material testing, finished product testing, stability testing, water testing, media preparation, growth promotion of media, antibiotic microbial assay testing, microbial identification, method development testing, suitability testing, antimicrobial effectiveness testing, and other microbial testing as needed.
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Work with various analytical methods including cleaning verification, assay and related substances, dissolution, residual solvents in-process control, and analysis of finished products and excipients.
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