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Expertise in cell culture/fermentation or purification unit operations. Support the development of technology transfer plans and manage transfer from Process Development and into the selected manufacturing site (internal or external) in partnership with Process Development, Analytical Development, Quality, and the Manufacturing Operations.
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The Manufacturing Associate I/II participates in the manufacturing of biopharmaceutical drug product to support MacroGenics' multiple clinical programs in the Protein Purification area. Knowledge of protein purification techniques.
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Expertise in protein purification, nanoparticle purification, or virus-like particle (VLP) purification techniques. We are currently seeking a highly motivated and experienced Senior Scientist to join our Downstream Process Development group.
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Background in molecular biology techniques such as cloning, site-directed mutagenesis, DNA and RNA isolation and purification, sequencing, RT-PCR, and qPCR. Background in molecular biology techniques such as cloning, site-directed mutagenesis, DNA and RNA isolation and purification, sequencing, RT-PCR, and qPCR.
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Experience with mammalian cell culture, production and/or purification desired. Great opportunity to be part of a dedicated team serving the rapidly expanding cell and gene therapy (CGT) market.
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Small molecule, biologics, in vitro, hybridoma, protein expression, protein purification #LI-CP1 #LI-ONSITE. Responsibilities for the Senior Scientist include:·Utilize phage/yeast display or hybridoma technologies to discover antibody hit molecules used in neurology research.
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Principal Scientist, Protein Purification. Plasmid design and construction, and protein purification. Lead VLP protein purification efforts, ensuring high standards of quality and efficiency.
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The successful candidate will play a crucial role in leading drug substance purification process development, scale-up, and technology transfer activities for the pipeline molecules, contributing to the successful manufacturing of biopharmaceutical products, with a specific expertise and focus on antibody-based molecules including antibody-drug conjugates (ADCs), bispecific antibodies and fusion proteins.
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AstraZeneca is seeking an initiative-taking leader for biologics process development with a focus on upstream operations.
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Required Knowledge, Skills and Abilities: Knowledge of molecular biology techniques, tissue culture, handling of infectious agents, nucleic acid and protein extractions, purification and characterization.
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Help troubleshoot and optimize protein engineering, expression, purification, and formulation processes. BS/MS degree in Protein Biochemistry, Molecular Biology, or similar. Protein biochemistry and molecular biology experience.
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Perform bulk-synthesis, purification, and formulation efforts for advanced testing in animal models. Perform chemical and biochemical reactions and appropriate analytical analyses, including chemical synthesis and optimization of small molecules probes and organic synthesis of key materials such as reference compounds.
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Essential Requirements Background in molecular biology techniques such as cloning, site-directed mutagenesis, DNA and RNA isolation and purification, sequencing, RT-PCR, and qPCR. Experience in cell culture, viral propagation, and viral titration.
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In molecular biology techniques such as cloning, site-directed mutagenesis, DNA and RNA isolation and purification, sequencing, RT-PCR, and qPCR. in molecular biology techniques such as cloning, site-directed mutagenesis, DNA and RNA isolation and purification, sequencing, RT-PCR, and qPCR.
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Main Duties & Responsibilities This position is a laboratory-based role, the main responsibility will be the development of conjugation and purification processes for antibody-drug conjugates (ADCs.
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fermentation purification jobs in Gaithersburg, MD
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