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Experience with pharmacodynamics assays of mouse tissue, including Western Blotting, ELISA/Mesoscale and flow cytometry is a plus. Optimize and perform studies to define target biology in mouse models of inflammation and immunity for in vivo in vitro and ex vivo.
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You have experience designing and executing experiments utilizing multiparameter flow cytometry. The Team Alloy’s Translational Research team supports our drug discovery partners with in vitro and in vivo testing of therapeutic drug candidates across multiple modalities.
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Expertise in primary human cell culture, multi-color flow cytometry, multiplex cytokine detection, functional immune cell assays (proliferation, cytotoxicity, chemotaxis) and assay development is essential.
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Perform experiments involving the in vitro screening and characterization of antibody and biologics-based drug candidates using various immunological, biochemical, and cell-based assays (e.g., ELISA, MSD, BLI, flow cytometry.
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Proficiency in mammalian cell culture techniques, flow cytometry, qPCR, DNA and RNA extraction, transfection, ELISA, and western blotting. The Senior Research Associate/Associate Scientist will be a key contributor in our research efforts in delivering our novel gene writing technologies to target tissues *in vitro.
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Participate in the construction and screening of antibody libraries through immunization, antibody display, flow cytometry and repertoire analysis using NGS. Advanced experience in biochemical techniques (including BLI, SPR, and/or flow cytometry.
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Extensive experience in preclinical in vivo evaluation of T cell therapies with coupled expertise in ex vivo T-cell pharmacokinetic and pharmacodynamic readouts such as T-cell persistence, immunophenotype, biodistribution (by flow cytometry and IHC), cytokine release.
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Perform and optimize protein expression assays including immunofluorescence and flow cytometry to support in vitro and in vivo studies. Hands on experience with cell-based immunoassay techniques including immunofluorescence and flow cytometry.
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Development and application of molecular and cell-based assays (e.g., gel electrophoresis, PCR, qPCR, ddPCR, ELISA, western blot/Jess, flow cytometry, MSD) Experience in cell-based assays (e.g. flow cytometry, luminescence assays, etc.
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Participate in the construction and screening of immune-based libraries through immunization, antibody display, and flow cytometry. Visterra, Inc., is seeking a highly motivated Research Associate with research experience in biochemistry, cellular and/or molecular biology to help discover and develop biologic therapeutics, as well as expand platform technologies that support our antibody-based drug discovery programs.
$78,000 - $83,500 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Perform multiple biological techniques, including tissue culture, cell transfection, live cell imaging, qPCR, flow cytometry, western blots, ELISAs, capillary electrophoresis, and other biochemical assays.
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Hands-on experience with cell-based and molecular biology assays, such as dPCR, ELISA/MSD, flow cytometry, imaging-based assays etc. We are seeking a highly motivated and skilled Research Associate who will be responsible for developing and performing in-vitro and ex-vivo biomarker assays to deliver translational science datasets across multiple programs within pioneering medicines.
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In vitro procedures and assays include but not limited to1) primary cells isolation from blood, 2) tissue digestion and dissociation, 3) Immunophenotyping by flow cytometry and cell sorting, 4) ELISA or MSD-based cytokines analysis, 5) Cell culture and functional assays such as proliferation and apoptosis.
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Experience in designing and executing flow cytometry protocols. We’re open to multiple levels for this role, from Associate Scientist to Senior Scientist. Contribute to or lead external CRO programs, such as in vivo studies.
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Characterize gene and protein expression using techniques such as flow cytometry, western blotting, qPCR, and ELISA. Pinetree Therapeutics is currently seeking a highly skilled and self-motivated Research Associate, with a strong emphasis on in vivo techniques, to join our dynamic research team.
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vivo flow cytometry associate jobs in Waltham, MA
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