Flagship Pioneering

We are seeking a highly motivated and skilled Research Associate who will be responsible for developing and performing in-vitro and ex-vivo biomarker assays to deliver translational science datasets across multiple programs within pioneering medicines.. Previous experience with assay development to evaluate translational pharmacology in rodent, NHP and human tissues/plasma/whole blood is highly desired.. Perform ex-vivo and in-vitro laboratory assays to support translational research activities characterizing novel therapeutics.. Previous experience with ex-vivo assay development in rodent, NHP and human tissues/plasma/whole blood. Hands-on experience with cell-based and molecular biology assays, such as dPCR, ELISA/MSD, flow cytometry, imaging-based assays etc.

senior research associate

What if... We could harness the power of Flagship’s scientific platforms and create novel treatment options that benefit more patients, sooner? Pioneering Medicines, an initiative of Flagship Pioneering, is building a world-class biopharmaceutical R&D capability focused on conceiving and developing life-changing treatments for patients by harnessing the power of Flagship's scientific platforms and applying those innovative approaches to serious diseases with unmet medical need. Unique to Pioneering Medicines’ approach is the opportunity to combine platforms to create truly novel and potentially transformative treatments. About Flagship Pioneering: Flagship Pioneering conceives, creates, resources, and develops first-in-category life science platform companies to transform human health and sustainability. Since its founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures, resulting in over $34 billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents. Position Summary: We are seeking a highly motivated and skilled Research Associate who will be responsible for developing and performing in-vitro and ex-vivo biomarker assays to deliver translational science datasets across multiple programs within pioneering medicines. This position supports translational research activities aimed at bridging the gap between early research and clinical development. The ideal candidate will be skillful in conducting in vitro and ex-vivo characterization of novel therapeutics and cell-based assays using both rodent, NHP and human cell lines and primary cells. Previous experience with assay development to evaluate translational pharmacology in rodent, NHP and human tissues/plasma/whole blood is highly desired. The position will require ability to work in a fast-paced environment on multiple tasks, quickly learn new techniques, organize tasks efficiently and keep records accurately. Ability to interact well with scientific colleagues and work effectively in a team-oriented environment will be necessary. This role is a 12-month contract. Pioneering Medicines 3rd party agency will be hiring for this position. Employees under this position with be working at Pioneering Medicines as a contractor with the possibility to convert to a full-time Pioneering Medicines employee based on performance and other criteria in the future. Responsibilities: <ul><li>Perform ex-vivo and in-vitro laboratory assays to support translational research activities characterizing novel therapeutics. </li><li>Independently conduct experiments and analyze data. </li><li>Operate and maintain the relevant equipment. </li><li>Maintain electronic notebook. </li></ul>Requirements: <ul><li>Bachelor or Master of Science degree with a minimum of 2 years’ experience in a laboratory of academia or industry. Industrial experience is preferred. </li><li>Previous experience with ex-vivo assay development in rodent, NHP and human tissues/plasma/whole blood</li><li>Experience working with sterile cell culture techniques for the growth and maintenance of cell lines and primary cells (e.g. peripheral blood mononuclear cells, organoids, explant cultures)</li><li>Prior working experience with in vitro cell based pharmacology assays using human or rodent primary cells. </li><li>Hands-on experience with cell-based and molecular biology assays, such as dPCR, ELISA/MSD, flow cytometry, imaging-based assays etc. </li></ul>Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background. Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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