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As part of the Discovery Biotherapeutics efforts at BMS, the Principal Scientist will play a key role in advancing antibody drug conjugates technologies at BMS. Experience in analytical characterization of ADCs including SEC, RP-HPLC, LC-MS, CE-SDS, ELISA, DSC, and HIC.
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Extensive experience with pharmacokinetic and biodistribution studies of antibody-drug conjugates and relevant analytical methods including LC-MS/MS for small molecule quantitation and MSD for ELISA and LBbased assays.
Full-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Development, optimization, qualification, transfer, validation, and routine execution of analytical methods for proteins, mAbs, drug conjugates using techniques pertinent to LC (SEC, RP, IEX), LCMS, ELISA, CE-SDS, icIEF, and other wet chemistry techniques.
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Familiarity with protein-related characterization assays and biophysical techniques, including ELISA, flow cytometry, Octet/Biacore, and SDS-PAGE. Support in vitro and in vivo studies by performing small-/medium-scale antibody productions.
InternExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Ability to establish and perform biochemical and molecular assays, including ELISA/MSD, qPCR, BCA and other relevant techniques. Perform biochemical and molecular biology assays to enable PK/PD analysis of therapeutic candidate drugs, including ELISA/MSD, and qPCR.
$48 an hourExpandApply NowActive JobUpdated 3 days ago - UpvoteDownvoteShare Job
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Scientists from world-class universities, aim to improve the quality of life science research by providing high-quality antibodies, proteins, ELISA kits, NGS Prep Kits, and molecular enzymes. A fundamental understanding of antibody and molecular enzyme products is required.
Full-timeExpandApply NowActive JobUpdated 15 days ago - UpvoteDownvoteShare Job
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Primary Responsibilities Include: Development, optimization, qualification, transfer, validation, and routine execution of analytical methods for proteins, mAbs, drug conjugates using techniques pertinent to LC (SEC, RP, IEX), LCMS, ELISA, CE-SDS, icIEF, and other wet chemistry techniques.
ExpandApply NowActive JobUpdated 4 days ago - UpvoteDownvoteShare Job
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Experience using various flow cytometry/FACS instruments for screening antibody libraries. Binding assays based on FACS, flow cytometry and ELISA. As an expert in biologics drug discovery, you will be primarily responsible for identifying progressable hits from our bespoke AI designed antibody libraries using eukaryotic display technologies or high-throughput antibody generation and screening.
Full-timeExpandApply NowActive JobUpdated 17 days ago - UpvoteDownvoteShare Job
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Understanding of principles of binding assays (like ELISA) and serum antibody-based neutralization assays. Get trained and subsequently apply hands-on expertise with cell-based neutralization assays using cell lines as well as possibly ELISA, MSD, Luminex, other binding and flow cytometry-based assays.
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Support key experiments by maintaining a broad range of cell lines and conducting cell-based bioassays such as antibody internalization using flow cytometry or cytotoxicity. Perform and enable high throughput characterization of antibodies and proteins including HPLC analysis, binding by bio-layer interferometry and ELISA, and other functional assays.
InternExpandApply NowActive JobUpdated 15 days ago - UpvoteDownvoteShare Job
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Modalities include FACS, ELISA, Luminex, Octect, (RT)-qPCR and related microfluidic and digital technologies, Next Generation Sequencing (2nd and 3rd generations), direct nucleic acid detection (CRISPR/Cas, NanoString, QuantiGene, and others.
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Conduct experiments to critically assess in vitro assays (e.g. DNA/RNA/protein extraction, RT-PCR, RT-qPCR, ddPCR, western blot, ELISA, immunostaining, imaging, etc.) Through this proprietary, versatile and modular approach, Entrada is advancing a robust development portfolio of RN, antibody- and enzyme-based programs for the potential treatment of neuromuscular, ocular, metabolic and immunological diseases, among others.
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Execute antibody and protein engineering strategies to generate novel and stable AND-Body molecules. Ampersand Biomedicines, Inc. is looking for a highly motivated, goal-driven and collaborative Senior Research Associate with expertise in molecular cloning, protein / antibody engineering, expression, purification, and biophysical analysis to join our dynamic Protein Sciences team.
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Perform basic laboratory techniques including luciferase reporter assays, ELISA/MSD/Luminex assays, PCR/qPCR and automated Western Blot. Characterize the immune response in primary cell-based assays, support biology read outs from in vivo mouse models including analysis of cytokine/chemokine secretion, antibody secretion, and flow cytometry analysis.
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In depth understanding and some hands-on experience in one or more of the following areas is required: Cell-Based cytotoxicity or potency assay, ELISA, spectroscopy (UV/Vis), binding affinity (SPR, Octet, etc.
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elisa antibody jobs in Waltham, MA
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