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You will be a key team member responsible for utilizing NextMAP TM , a NextRNA proprietary computation engine that identifies driving disease lncRNAs∯*∯ You will have an opportunity to work with a diverse team of bioinformaticians, biochemist, chemists, and biologist to support drug discovery programs for next wave of RNA therapeutics.
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With a combination-focused pipeline that exploits the power of six scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy and Epigenetics) to help address unmet clinical needs in a host of hematological cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death.
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The position will provide a unique opportunity to play a critical role in the advancement of FL89’s computational discovery and preclinical platforms, through the development of disruptive approaches for biotherapeutic drug discovery.
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Experience preferable in pharmaceutical R&D setting with knowledge of the drug discovery process and the practice of laboratory animal medicine. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.
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The Vice President of Business Development will engage with pharmaceutical companies and hospitals to commercialize Pear Bio’s precision medicine platform and drug discovery pipeline. Our patient data, biobank and biomarker technology have led to the creation of an in-house drug discovery pipeline for cancers with high unmet need.
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Perform integrative analysis of multiple biomarker assessments including gene expression, IHC/Multiplex IF data, safety biomarker, and drug response data for baseline and post-dose biomarker discovery for clinical programs.
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Degree in Cheminformatics, Computational Chemistry, Computer Sciences or related quantitative preferred Relevant experience includes: Research experience in the field of small molecule drug discovery within industry or academia (industry preferred) as demonstrated by publications or presentations documenting impactful application of computational chemistry methods.
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BUSINESS AREABiologics Engineering (BE) is large global organization with teams in Cambridge, UK and Gaithersburg MD responsible for the discovery and optimization of next generation biologics to create biological drug candidates for all key therapeutic areas such as oncology, respiratory and inflammation, cardiovascular, renal and metabolic diseases.
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The AI & Computational Science (AICS) team at Novartis Biomedical Research is dedicated to revolutionizing drug discovery through AI. Our mission is to accelerate the development of transformative medicines for patients worldwide.
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A successful candidate will have had experience with preclinical drug discovery including immunoassays, flow cytometry, cell cytotoxicity assays, and ex vivo cell-based assays. Must be able to work independently and have an understanding of the preclinical drug discovery process.
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The ideal candidate will be contributing towards in vitro / in vivo BA and biomarker (BM) quantitation studies along the drug discovery path using cell-culture, quantitative bioanalysis and related lab skills, especially for early-stage programs in the company portfolio.
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EProtein promises to be a breakthrough protein expression, characterization and purification technology that brings rapid protein access to the life science benchtop and accelerates drug discovery process.
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Experience with AAV gene therapy drug development, bench to bedside and with biologics drug discovery and development. Voyager’s TRACER™ AAV capsid discovery platform has generated novel capsids with high target delivery and blood-brain barrier penetration at low doses, potentially addressing the narrow therapeutic window associated with conventional gene therapy delivery vectors.
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PhD or equivalent degree in Pharmaceutical Sciences, Molecular Biology, Chemistry, Biochemistry or Pharmacology with experience in drug discovery, or a higher degree in a research area relevant to DMPK science.
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Will interact and closely collaborate with other Small Molecule Unit Scientists (medicinal chemists), Data Science & Innovation (DSI) computational chemists, Global Drug Discovery (GDD) biology, Global Drug Discovery and Safety (GDDS); Global Research Technologies (GRT.
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drug discovery jobs in Somerville, MA
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