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The ideal candidate will have hands-on experience working with mammalian cell culture, protein expression, purification and analytical QC using diverse biochemical methods such as ELISA, SDS-PAGE, Western blotting.
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Understanding and hands-on experience in one or more of the following areas with biological molecules are required: ELISA, gel electrophoresis, chromatography (LC-based), spectroscopy (UV/Vis), binding affinity (SPR, Flow cytometry, Octet, etc.
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Expertise in Ligand Binding Assay Methods (ELISA, MSD, Gyrolabs, Simoa etc.) Working knowledge of skills in PCR methods, LCMS, Flow cytometry are highly desirable. Moderna's Bioanalytics group is seeking an Associate Director with strong hands-on experience in ligand-binding assays, including pharmacokinetics (PK), pharmacodynamics (PD), and anti-drug antibody (ADA) assessments, to quantify mRNAs, proteins, and antibodies against therapeutic proteins.
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Experience with tissue culture, cell-based, and molecular assays (e.g. western, Q-PCR, ELISA, CTG) Be responsible for the assessment and analysis of cancer and immune cell function and phenotype using multicolor flow cytometry, ELISA, western blotting, gene expression analysis, and other cell-based assays.
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Characterize recombinant proteins using SDS-PAGE, WB, protein quantitation, HPLC, ELISA and other biochemical/biophysical assays such as BLI and SPR to determine protein purity and function. Characterize recombinant proteins using SDS-PAGE, WB, protein quantitation, HPLC, ELISA and other biochemical/biophysical assays such as BLI and SPR to determine protein purity and function.
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Familiarity with ELISA, MSD, qPCR/RT-qPCR, ddPCR and flow cytometry would be a plus. Familiarity with ELISA, MSD, qPCR/RT-qPCR, ddPCR and flow cytometry would be a plus. On track to graduate with a B.S. or M.S. in Biochemistry, Chemical Engineering, Molecular Biology, Bioengineering, Molecular Medicine, Genetics or related field.
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Assist in interpretation and troubleshooting of analytical assays in various platforms including, flow cytometry, ELISA/MSD, qPCR and ddPCR. Collect and interpret data, prepare experimental reports, and present findings to the IO Process team.
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Strong understanding of analytical techniques using HPLC, ELISA and mass spectrometry based methods. Additional experience in downstream purification of biologics including chromatography separations and filtration operations (depth, dead-end, and ultrafiltration/diafiltration) is a plus.
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Provide assistance in the execution of experiments and analytical procedures including: molecular biology, DNA cloning, cell culture, protein production, ELISA, Biolayer interferometry and HPLC.
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Exclusive preferred pricing on Peloton fitness equipment. Strong knowledge of Bioanalytical Assay Validation regulations (FDA, EMA guidance) Minimum of 5-10 years of hands-on experience in Bioanalytical Method Development, qualification, validation, and sample analysis to support GLP/nGLP studies.
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The key functions for this lab-based role is to perform cell-based experiments to assess the performance of our novel RNA molecules and to conduct the end-point assays for various in vivo experiments (e.g. ELISA, MSD, flow cytometry.
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Biochemical and/or analytical assays (ELISA, SPR, BLI, SDS-PAGE). Visterra, Inc., is seeking a highly motivated Research Associate with research experience in biochemistry, cellular and/or molecular biology to help discover and develop biologic therapeutics, as well as expand platform technologies that support our antibody-based drug discovery programs.
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Proficiency in tissue culture, cell engineering, and flow cytometry is preferred, experience with ELISA and cytotoxicity assays using Incucyte desired. Proficiency in tissue culture, cell engineering, and flow cytometry is preferred, experience with ELISA and cytotoxicity assays using Incucyte desired.
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Proficient in molecular and cell based analytical methods including cell culture, In vitro cell based assays, ddPCR, ELISA, and flow cytometry. Proficient in molecular and cell based analytical methods including cell culture, In vitro cell based assays, ddPCR, ELISA, and flow cytometry.
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Expertise in in vitro transcription, analytical tools of RNA (gel electrophoresis, enzymatic reactions, immunoblotting, ELISA, qPCR and/or ddPCR) Proficiency in in vitro transcription/translation systems and in vivo cell based reporter assays.
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