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Biogen is looking for an innovative and dedicated scientist to become the Director/Head of the Tissue-Enhanced Delivery Technologies group, who will lead direct reports as well as a cross-functional effort to identify and validate novel methods for enhancing delivery of biologics, oligonucleotides (including ASOs), and gene therapy modalities to tissues including muscle and brain.
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Job Summary: As a Field Application Scientist specializing in Advanced Microscopy Applications for Cell and Tissue Biology, you will be at the forefront of translating cutting-edge microscopy technologies into impactful solutions for researchers in life sciences.
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The Research Associate I/II will be responsible for tissue culture and *in vitro. transfections, tissue processing from *in vivo. Process and homogenize animal cells and tissue for the isolation of proteins and/or nucleic acids.
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Prior experience implementing precision medicine approaches in clinical trials including companion diagnostic (CDx) development experience in liquid-based and tumor tissue-based approaches. Broad technical expertise/knowledge including with flow cytometry, ELISA, immunohistochemistry, qRT-PCR, NGS and RNA Seq.
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Knowledge of human cell, tissue, and cellular and tissue-based products (HCT/P), or cell and gene therapy production is desirable. The Role: The Senior Scientist, QC Microbiology will perform assay development, characterization, optimization, transfer, qualification, verification, validation and investigation for QC Microbiology group.
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Experience with tissue processing. The current Flagship ecosystem comprises 41 transformative companies, including Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Foghorn Therapeutics (NASDAQ: FHTX), Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Sigilon Therapeutics (NASDAQ: SGTX.
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With its proprietary FORCE platform, Dyne is developing modern oligonucleotide therapeutics that are designed toovercome limitations in delivery to muscle tissue. The Chief Information Officer (CIO) is a key role responsible for defining and evolving Dyne’s technology and digital strategy, vision, and roadmap in line with the business strategy, to drive innovation, efficiency, and competitive advantage to enable organizational success, growth, and commercial readiness.
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This includes cell-based assays, tissue culture, biochemical assay technologies, and protein and RNA expression analysis. Tasks include drug administration via multiple routes (IV, IP, SC, PO etc), blood and tissue collection, and tumor volume measurement.
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Transports tissue samples between collection site, processing site, and MGH laboratories. Under the DPRB protocol, we ask subjects with neurological movement disorders to provide cross-sectional and longitudinal medical and family history information, neurological examination(s) and tissue samples to be used in wide-ranging research applications.
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Experience with cell and molecular biology techniques, including tissue culture, RNA and protein extraction from cell and tissue samples, immunological techniques such as ELISA (MSD), Western blot, as well as qPCR, and other standard laboratory techniques.
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Proficiency in tissue culture, cell engineering, and flow cytometry is preferred, experience with ELISA and cytotoxicity assays using Incucyte desired. Proficiency in tissue culture, cell engineering, and flow cytometry is preferred, experience with ELISA and cytotoxicity assays using Incucyte desired.
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Job Description TECHNICAL ASSOCIATE II, Biological Engineering (BE), to join the , a major focus of which is building human “organs-on-chips” to model liver metabolic diseases, gut/microbiome, and chronic infection (Lyme and tick-borne diseases), some of which involve human patient specimens and working with stem cells and tissue engineering; and collaborating on building models of liver metabolic diseases.
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We are seeking a highly motivated scientist with extensive research experience in image analysis and feature extraction of H&E and/or immunohistochemistry (IHC) stains to join our Computational Tissue Imaging Research team in the Translational Bioinformatics group.
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Experiments include mammalian tissue culture, expansion and differentiation of human induced pluripotent stem cells (hIPScs), fluorescent microscopy, and preparing special materials. Some mammalian tissue culture experience preferred QUALIFICATIONS: BS or BA in a biological/physical science with relevant course or project work required.
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The person will perform animal husbandry including genotyping and weaning pups, animal experiments including T cell transfer and tumor implantation, laboratory experiments including tissue culture, RNA and DNA preparation, qRT-PCR, tissue preparation and histological analysis, flow cytometry on a routine basis.
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bathroom tissue jobs in Newton Lower Falls, MA
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