Flagshippioneering

The Research Associate I/II will be responsible for tissue culture and *in vitro. transfections, tissue processing from *in vivo. Familiarity with molecular biology and biochemical assays such as: ELISAs, luciferase or fluorescent protein reporter assays, and Western blotting. Experience with lipid nanoparticles. The current Flagship ecosystem comprises 41 transformative companies, including Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Foghorn Therapeutics (NASDAQ: FHTX), Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Sigilon Therapeutics (NASDAQ: SGTX).

research associate i

**Company Summary:**Tessera Therapeutics is pioneering Gene Writing a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy. Tessera Therapeutics was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.**Position Summary**:The Research Associate I/II will be responsible for tissue culture and *in vitro* transfections, tissue processing from *in vivo* mouse studies, and downstream assays to measure effective delivery and efficacy of our Gene Writer platforms. This individual will conduct lipid nanoparticle transfections and perform high-content and confocal microscopy analyses and cellular response assays. In addition, the Research Associate I/II is expected to contribute to laboratory upkeep and cultivate a positive and comfortable working environment. We are searching for a driven, curious, enthusiastic, and self-motivated individual. This individual will join a dynamic, rapidly growing, and highly collaborative team.**Key Responsibilities:**The successful candidate will work both independently and as part of a collaborative team to:* Culture mammalian cell lines and primary cells* Perform lipid nanoparticle, mRNA, and plasmid transfections and viral vector transductions* Experience with microscopy of mammalian cells* Process and homogenize animal cells and tissue for the isolation of proteins and/or nucleic acids* Prepare data summaries, protocols, and quantitative analyses* Maintain thorough and detailed electronic lab notebooks and documentation records* Assist in organization of samples, test material, and reagents related to the teams research**Basic Qualifications:*** B.A./B.S. in cell biology, molecular biology and/or related fields with 1-2+ years industry research experience or MS with 0-2 year industry experience* Experience with mammalian cell culture* Familiarity with molecular biology and biochemical assays such as: ELISAs, luciferase or fluorescent protein reporter assays, and Western blotting* Excellent troubleshooting capability, attention to detail, and creative ideas* Ability to work independently and as part of a team* Strong communication and presentation skills* Excellent organization, record-keeping, and time management**Preferred Qualifications:*** Experience with lipid nanoparticles* Experience with tissue processing* Experience with mammalian cell culture* Experience with gene addition and/or editing**More About Flagship Pioneering**Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has, through its Flagship Labs unit, applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $50B in aggregate value. To date, Flagship has deployed over $2.2B in capital toward the founding and growth of its pioneering companies alongside more than $18B of follow-on investments from other institutions. The current Flagship ecosystem comprises 41 transformative companies, including Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Foghorn Therapeutics (NASDAQ: FHTX), Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Sigilon Therapeutics (NASDAQ: SGTX).Flagship Pioneering and our ecosystem companies are **committed to equal employment opportunity** regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.***Recruitment & Staffing Agencies:*** *Flagship Pioneering and its affiliated Flagship Lab companies (collectively, FSP) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneerings internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.*

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