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Perform protein characterization to identify biomarkers including multiplex ELISA, microarray or mass spectroscopy is a plus. Interpret material characterization tests including tensile strength, Rheology, DMA, viscosity, spectroscopy, or dynamic light scattering (DLS.
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Experience with ELISA/ WB, IHC/ Immunofluorescence and microscopy is a plus. Experience in therapeutic drug discovery, gene therapy or RNA therapeutics. Experience with ELISA/ WB, IHC/ Immunofluorescence and microscopy is a plus.
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Experience with molecular biology techniques such as DNA and RNA extraction, qPCR, protein quantification, ELISA, and enzymatic assays is required. Experience with molecular biology techniques such as DNA and RNA extraction, qPCR, protein quantification, ELISA, and enzymatic assays is required.
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Significant experience with cell and gene therapy test methodologies (PCR, Flow Cytometry, ELISA, and cell-based assays). Significant experience with cell and gene therapy test methodologies (PCR, Flow Cytometry, ELISA, and cell-based assays.
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General knowledge on protein purification, protein conjugation, HPLC analysis, SDS-PAGE analysis and mass spectrometric analysis of protein. The purification group is responsible for non-GMP protein-drug lead generation, supporting the various Pharmaceutical research units and their pre-clinical therapeutic in-vitro and in-vivo needs.
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A deep understanding of PK and ADA assay development principles and techniques (ELISA, MSD, BLI, SPR, MS, %recovery) with precision and accuracy. A deep understanding of PK and ADA assay development principles and techniques (ELISA, MSD, BLI, SPR, MS, %recovery) with precision and accuracy.
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Performs Bio-Analytical testing such as Flow Cytometry, ELISA, qPCR, cell count, (incoming, in-process and final product release testing). The Senior QC Analyst position interacts regularly with TScan’s Quality Assurance, Analytical Development, Process Development, Manufacturing, Facilities, as well as TScan’s external test laboratories, where applicable.
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Experience using analytical techniques such as SDS-PAGE, RP-HPLC, ion exchange and size exclusion chromatography, LC-MS, UV-vis to characterize protein ligands and conjugates, underscoring a well-rounded understanding of protein characterization methods.
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Skills: HPLC, SOP, In Vitro, In Vivo, Protein Purification, GMP (Good Manufacturing Practice) The purification group is responsible for non-GMP protein- drug lead generation, supporting the various company research units and their pre-clinical therapeutic in- vitro and in- vivo needs.
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The purification group is responsible for non-GMP protein- drug lead generation, supporting the various research units and their pre-clinical therapeutic in- vitro and in- vivo needs. Qualified candidate will play an essential role in a high-energy protein purification research laboratory within BioMedicine Design.
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Demonstrated experience in cell culture, flow cytometry and other related immune assays such as ELISA, PCR, and cell-based assays is required. Demonstrated experience in cell culture, flow cytometry and other related immune assays such as ELISA, PCR, and cell-based assays is required.
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Strong expertise in immunological techniques and assay design/ development, including flow cytometry, ELISA, electrochemiluminescent (ECL) assays, cell-based assays such as ELISPOT and/or ASC assays, and animal models.
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Experience with a subset of techniques such as: protein labeling/biotinylation, ELISA/MSD, analytical HPLC, light scattering methods (MALS/DLS), DSF, SPR (Biacore) or other methods of measuring binding kinetics and affinity, Pymol.
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Performs multiple bioanalytical testing assays such as flow cytometry, ELISA, qPCR, cell count, and rapid USP safety assays (sterility, endotoxin, mycoplasma). Performs multiple bioanalytical testing assays such as flow cytometry, ELISA, qPCR, cell count, and rapid USP safety assays (sterility, endotoxin, mycoplasma.
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By Luminex and/or ELISA assays and other procedures as defined. Education: Bachelor's degree or equivalent in a biological science or chemistry or Medical Laboratory Scientist (MLS), Medical Technologist (MT), Clinical Laboratory Scientist (CLS) or equivalent certification.
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