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Expertise in Ligand Binding Assay Methods (ELISA, MSD, Gyrolabs, Simoa etc.) Working knowledge of skills in PCR methods, LCMS, Flow cytometry are highly desirable. Moderna's Bioanalytics group is seeking an Associate Director with strong hands-on experience in ligand-binding assays, including pharmacokinetics (PK), pharmacodynamics (PD), and anti-drug antibody (ADA) assessments, to quantify mRNAs, proteins, and antibodies against therapeutic proteins.
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By Luminex and/or ELISA assays and other procedures as defined. Education: Bachelor's degree or equivalent in a biological science or chemistry or Medical Laboratory Scientist (MLS), Medical Technologist (MT), Clinical Laboratory Scientist (CLS) or equivalent certification.
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Provide assistance in the execution of experiments and analytical procedures including: molecular biology, DNA cloning, cell culture, protein production, ELISA, Biolayer interferometry and HPLC.
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Exclusive preferred pricing on Peloton fitness equipment. Strong knowledge of Bioanalytical Assay Validation regulations (FDA, EMA guidance) Minimum of 5-10 years of hands-on experience in Bioanalytical Method Development, qualification, validation, and sample analysis to support GLP/nGLP studies.
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Proficiency in tissue culture, cell engineering, and flow cytometry is preferred, experience with ELISA and cytotoxicity assays using Incucyte desired. Proficiency in tissue culture, cell engineering, and flow cytometry is preferred, experience with ELISA and cytotoxicity assays using Incucyte desired.
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Biochemical and/or analytical assays (ELISA, SPR, BLI, SDS-PAGE). Visterra, Inc., is seeking a highly motivated Research Associate with research experience in biochemistry, cellular and/or molecular biology to help discover and develop biologic therapeutics, as well as expand platform technologies that support our antibody-based drug discovery programs.
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Performing protein-based laboratory techniques, including antibody modifications, ELISA, buffer formulations and assay optimization. Performing protein-based laboratory techniques, including antibody modifications, ELISA, buffer formulations and assay optimization.
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Broad technical expertise/knowledge including with flow cytometry, ELISA, immunohistochemistry, qRT-PCR, NGS and RNA Seq. Broad technical expertise/knowledge including with flow cytometry, ELISA, immunohistochemistry, qRT-PCR, NGS and RNA Seq.
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Experience with SEC-HPLC, DLS, ddPCR/qPCR, Western blot, ELISA, spectroscopic and bioassay techniques. This 6-month position centers on drug substance process development for gene therapy but will interface with a broader team of vector and cell line engineering, upstream process development, analytics, and clinical manufacturing support.
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Experience with molecular biology assays (ELISA, PCR, protein expression, phage display, next-gen sequencing, cell culture); Responsibilities will include development and in vitro evaluation of drug delivery formulations - namely small molecule therapeutics and mRNA nanomedicines - and devices (~50% effort), and support preclinical evaluation of technologies in small and large animal models (~50% effort.
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Experience with analytical methods (HPLC, LC-MS, SPR, XRD, CD, ICP); B.S./B.A. in a relevant scientific field (e.g., molecular biology, pharmaceutical sciences, pharmacology, biomedical engineering.
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Significant experience with cell and gene therapy test methodologies (qPCR/ddPCR, Flow Cytometry, ELISA, and cell-based assays). Significant experience with cell and gene therapy test methodologies (qPCR/ddPCR, Flow Cytometry, ELISA, and cell-based assays.
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The ideal candidate should have relevant experience in T cell immunology, cancer cell culture and flow cytometry, and enjoy fast-paced, collaborative, and vibrant startup culture. TScan’s discovery platform is centered around a breakthrough technology that enables the rapid, comprehensive, and genome-wide identification of the peptide antigen targets of T cell receptors.
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Broad experience with cell-based assays and molecular techniques such as primary cell isolation/culture, multicolor flow cytometry, cell sorting, ELISA, qPRC, RNA and DNA isolation, immunoblot.
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Develop and optimize bioanalytical assays for the quantitative measurement of target proteins (ELISA, MSD). Skilled in molecular biology techniques (cloning, transfection, transduction, qPCR, CRISPR, RNAi, RNA seq, and western blot) Trained on various cell-based assays such as flow cytometry, cell proliferation, and immune functional assays.
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