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Strong subject matter expertise in immune-oncology, cell therapy drug discovery and development including CMC considerations, CAR design, engineering and armoring strategies, innate immune cells such as NK and gamma delta for the purposes of leading drug development projects from start to the clinic.
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Work closely with CROs and discovery DMPK to generate high quality data. Must have cultivated an appropriate attitude to deal with the challenges of drug development and experienced in regulatory interactions.
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As a Senior Scientist within the Research Analytics team you will help provide analytics solutions to inform compound discovery and prioritization for our early drug discovery platforms.
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Expertise in establishing binding assays for protein/protein or protein/small molecule interactions by SPR, DSF, ITC and/or MST and have applied these to small molecule drug discovery. You will be a Biophysics lead on projects and play a key role in drug discovery.
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Demonstrated track record of accomplishments, publications and conference presentations in computational chemistry and drug discovery. The successful candidate will play a leading role in developing medicinal chemistry optimization strategies for our most important drug discovery campaigns.
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We have developed a drug-discovery platform that integrates computational chemistry, structural biology, chemical biology, target-informed screening, and mechanism-driven pharmacology to develop small-molecule therapeutics that specifically modulate ferroptosis.
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Analytical Skill, Analytical Skill, Analytical Thinking, Chemical Biology, Chemistry, Clinical Trials, Communication, Curiosity, Data, Data Analysis, Design of Experiments (DOE), Detail-Oriented, Drug Development, Drug Discovery Process, Ethics, Gene Therapy, Group Problem Solving, Immunology, Inventory Management, Laboratory, Large Group Presentations, Leading Project Teams, Life Science, Machine Learning (Ml), Medical Research {+ 9 more.
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Qualified candidates must have a PhD in synthetic/organic chemistry or related scientific field with 15+ years’ experience in drug substance development and manufacturing and a proven track record in developing and scaling up chemical process to kilo lab, pilot plant and commercial plant scales.
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Biogen’s Translational Medicine Biomarkers Imaging group is actively engaged in an innovative and dynamic molecular imaging research program which includes the discovery and characterization of radiotracers and methodologies for application in drug development.
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Strong technical background at the bench in early stage drug discovery with a focus on chemistry/small molecule. Specific experience with either discovery chemistry, process chemistry, CMC, medicinal chemistry, or organic chemistry.
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A Senior Associate Scientist is responsible for organizing, conducting, and reporting non-GLP rodent toxicology, investigative, and pharmacokinetics/toxicokinetics (PK/TK) studies that support drug discovery and development.
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This is a unique opportunity for a PhD-level biologist to be involved in high-impact drug discovery projects in the newly developed Center for Therapeutic Discovery at Dana-Farber Cancer Institute.
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Plan, design and execute in-vivo pharmacological experiments to support and advance drug discovery programs in immunology and oncology. Effectively collaborate with integrated teams in a matrix organization setting to facilitate the conduct of studies and to the success of discovery programs.
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Our group utilizes innovative genomic technologies (i.e., pooled, and arrayed CRISPR screening, Optical Pooled Screening, Spatial Tx), and multi-omics approaches such as Perturb-Seq to impact all stages of the drug development pipeline from pre-clinical to clinical development.
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The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma. Family planning support up to $45,000 (e.g., IVF/PGT, adoption, surrogacy, egg retrieval.
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drug discovery jobs in Malden, MA
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