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As a Senior Scientist, Computational Biology - Cancer Biology at Harbinger Health, you will work collaboratively across all technical teams bringing expertise within cancer biology and NGS data analysis.
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Expertise in molecular and cellular biology techniques, such as ddPCR, virus production and transductions, confocal microscopy, immunohistochemistry, flow cytometry. Proficiency in RNA and DNA purification, qPCR, cloning and mammalian cell culture.
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Familiarity with commercially available NGS kits for targeted and non-targeted RNA & DNA sequencing. Must be skilled in the art of molecular biology especially in the field of next generation sequencing (NGS), carefully document every aspect of the work, have a strong sense for details, and capable of multitasking in a dynamic work environment.
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Experience in CLIA/CAP- processing patient samples- and manual molecular biology techniques, DNA/RNA extraction, qPCR, with pipetting at the very least. Current certification or eligible with ASCP (American Society of Clinical Pathologists) as an MLS - Medical Laboratory Scientist, MT - Medical Technologist, MLT-Medical Laboratory Technician, MB- Molecular Biology or specialist.
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As DNA sequencing is the foundational technology behind humanity‘s understanding of diseases and the tool that provides a new view into the fundamentals of biology, Volta is at the forefront of a sequencing revolution; driving sequencing towards seamless ease of use and complete automation.
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We are seeking motivated individuals with experience and familiarity with enzymatic synthesis, standard chromatography techniques, TFF, DNA purification kits, and molecular biology techniques such as DNA manipulations including PCR, ligations, restriction digestions, and plasmid cloning.
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PREFERRED: master’s degree; and experience with biochemical assays of hepatocyte function, basic biology laboratory methods (e.g., aseptic technique, mammalian cell culture, immunoassays, DNA and RNA isolation, colorimetric plate readers, microscopy, ELISAs, spectrophotometers), and other standard analytical equipment.
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Assist with ongoing projects in the laboratory which may involve performing the following activities: cloning, plasmid preps, PCR genotyping analysis, DNA and RNA extraction and purification, preparing samples for sequencing experiments, tissue culture, culturing of fungi and bacteria, microscopy, bioinformatics and/or data analysis.
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Proficiency in mammalian cell culture techniques, flow cytometry, qPCR, DNA and RNA extraction, transfection, ELISA, and western blotting. Familiarity with programs such as GraphPad Prism, FlowJo, and other molecular biology software/tools for data entry and analysis as well as well as PowerPoint for presentation.
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Operate and maintain automated liquid handlers for plasmid purification, as well as downstream QC applications like NGS and DNA normalizations. Conducting routine DNA characterization and quality control testing using techniques such as gel electrophoresis, fragment analysis, nanodrop, endotoxin testing, and preparation of samples for sequencing analysis (Sanger and NGS.
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Ph. D. with at least three years of industry or postdoc experience in Molecular Biology, Biotechnology or a similar field is required; or equivalent experience in an industry context with a Masters or Bachelor's degree.
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The BEP DNA production and protein expression group is looking for a laboratory technician to provide DNA production support for the protein expression and purification activities in BEP. The candidate is expected to have a strong background in molecular biology techniques and experience with nucleic acid production and analysis.
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Possess professional knowledge of Federal, State and local regulations pertaining to Center of Disease Control Prevention (CDC) and National Institutes of Health (NIH) guidelines for biosafety as they apply to infectious agents, recombinant DNA and bloodborne pathogens.
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You will develop and apply methods to process, analyze, visualize, and integrate large scale biological datasets, including whole genome DNA sequencing, whole transcriptome RNA sequencing, proteomics, metabolomics, and more.
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GENEWIZ LLC d/b/a Azenta Inc Lead the development of strategic go-to-market and technical sales product marketing approaches for company’s genomics, DNA sequencing and molecular biology products and services.
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dna biology jobs in Lexington, MA
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