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PhD or PharmD with relevant expertise in clinical pharmacology or pharmaceutical science is required. This position will work in close collaboration with different functions, including preclinical toxicology, preclinical pharmacokinetics, translational medicine, clinical, operations, and regulatory affairs.
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Utilize preclinical ADME, pharmacology, and pharmacodynamic data to develop predictions for human efficacious dose. Develop and validate preclinical PK/PD/Biomarker/Efficacy models to elucidate quantitative PK/PD relationships.
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Clinical Pharmacology and Pharmacometrics (CPP) provides characterization and prediction of the pharmacokinetics, pharmacodynamics and drug metabolism (PPDM) of the drug candidate in selected preclinical and all clinical areas, supporting drug discovery and medical therapeutics across many disease areas.
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As a central point of contact for discovery and preclinical research, this Associate Director will need to lead the design and interpretation of data ranging from in vitro target validation to in vivo development and then implement key data driven decisions.
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We are looking for someone exceptional to join our growing team as a Scientist I in the In Vivo Pharmacology group. Here at Kelonia Therapeutics, we aren’t just a preclinical company; we’re trailblazers in viral engineering, pushing the boundaries of in vivo lentiviral gene and cell therapy.
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Biocytogen Boston in vivo Team is seeking a talented, enthusiastic, highly motivated in vivo Pharmacologist to execute relevant disease models to support preclinical research services for biotech or pharma companies.
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The Toxicologist will collaborate with external vendors, the internal preclinical pharmacology and toxicology team, and other stakeholders across the company to ensure efficient processes that scale with Verve's continued growth.
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Solid understanding of drug metabolism, bioanalysis, pharmacokinetics, preclinical pharmacology, PK/PD modeling and clinical study designs. Review preclinical study reports, in conjunction with Pharmacokinetics/DMPK and prepare regulatory submission documentation.
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The Position We are looking for a highly motivated individual to be part of the preclinical pharmacology and toxicology team reporting to the Vice President of Toxicology. Be a thought partner providing scientific input for in vivo preclinical toxicology studies.
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Perform preclinical candidate screening of siRNAs leading to lead compound selection via combined in vitro and in vivo assays, working with or supported by cross-disciplinary groups, including chemistry, bioassay, histology, and in vivo pharmacology, and/or CROs.
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Head up the development team starting at the time of CTA/IND or proof of concept depending on the program, including all functions: clinical, regulatory, biostatistics, program management, clinical operations, tech ops/CMC, clinical pharmacology, research, and preclinical development, to design and execute clinical development plans for assigned projects.
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Ph. D./M.S. in clinical pharmacology, pharmacokinetics and metabolism, pharmacometrics, chemical/biomedical engineering, computational biology/chemistry or a related field with 0-5 years' pharmaceutical industry /academic experience.
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Within this internship project, the prospective intern will utilize preclinical and clinical datasets digitized from published literature and apply quantitative systems pharmacology (QSP) modeling approach to address relevant clinical and preclinical questions.
$20 - $46 an hourFull-timeExpandApply NowActive JobUpdated 3 months ago - UpvoteDownvoteShare Job
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Assay development to support preclinical and nonclinical efforts. · PhD in molecular biology, pharmacology, or related discipline with 1+ years of experience in pharmaceutical/biotech industry or 3+ years of experience as a post doc.
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Our client offers preclinical services for drug discovery, focused on the use of nonhuman primates to determine pharmacokinetics, pharmacology and toxicology of small molecules and biologics.
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pharmacology preclinical jobs in Cambridge, MA
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